Reconstruction of complex craniofacial defects by free flaps: Two case reports

Olusoga, O. O.; Nkemjika, Benjamin Nonso; Asoegwu, Chinyere N.; Kanu, Okezie Obasi; Ugburo, Andrew Omotayo; Mofikoya, Bolaji Oyawale

doi:10.4103/1117-1936.186298

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“…The relation between the clinical response and the interval between sessions could be attributed to the levels of TGFβ3 and IL10 that have a more profound and prolonged effect in the regeneration of the damaged tissues giving a good clinical response when the needling sessions are closer, 18,19 especially at intervals of 7 days 16 . However, Aust et al.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of microneedling depth of penetration in management of atrophic acne scars: a split‐face comparative study

El‐Domyati,

Moftah,

Ahmed

et al. 2023

Int J Dermatology

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BackgroundMicroneedling is a technique of repeated puncturing or drilling of the skin to induce repair and collagen induction. There are many reported important factors determining the efficacy of microneedling treatment. The extent of injury needed to produce the desired effect in each condition is one of these important factors.ObjectivesWe designed the present split‐face comparative study to evaluate the use and effectiveness of two different depths of penetration of Dermapen needles in the management of atrophic postacne scars.Patients and methodsThe present study involved 14 subjects with atrophic postacne scars. In each patient, both sides of the face were treated with six sessions of microneedling, using Dermapen at 2‐week intervals. A split‐face study design was performed. The right (Rt) side of the face was treated with Dermapen using 2.5 mm needle length, while the left (Lt) side was treated using 1.5 mm needle length.ResultsThere was a significantly better percentage of improvement of acne scars on the Rt side of the face compared to the Lt side (P = 0.02) after six sessions. Both sides of the face showed improvement of collagen bundles and elastic fibers characteristics after six sessions.ConclusionsThe use of 2.5 mm depth proved to be more effective both clinically and histologically in the management of atrophic postacne scars.

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Section: Discussionmentioning

confidence: 99%