Reconstruction of Acquired Breast Hypoplasia by Subcutaneous Scar Releasing and Repeated Fat Grafting Combination

Abstract

Summary:Breast hypoplasia may have a congenital or acquired etiology. One of the acquired reasons is postinfectious scars, which results in skin restriction and breast hypoplasia in the long term. Reconstruction of breast hypoplasia is performed by autologous tissues, implants, or both. In this report we present a hypoplastic breast reconstruction by subcutaneous scar releasing and multiple autologous fat grafting in a 21-year-old female with a right breast hypoplasia due to postinfectious scar. No complications were observed at 24 months follow-up after treatment by subcutaneous scar releasing and repeated (three times) fat grafting. Safe and natural reconstruction of mild breast hypoplasia due to fibrotic scars can be accomplished by performing a combination of subcutaneous scar releasing and multiple fat grafting.

From Bedside to Bench: The Effect of Muscular Denervation on Fat Grafting to the Breast by Comparing Take Rate, Quality, and Longevity

“…Despite very low postoperative complication rates, 22,28 disadvantages for patients undergoing AFG remain, including the unpredictable resorption rate and the risk of fat necrosis, oil cyst development, and calcifications. [28][29][30][31][32][33] This study indicates that, given an intact nerve, intramuscular injection results in unfavorable results compared with subcutaneous injection. If the nerve was cut or BTX treated; however, intramuscular injection appeared to be superior to subcutaneous injection.…”

Effects of Deferoxamine on Fat Graft Survival

“…22 Thus, recent studies about fat grafting were directed to increase the survival rates of fat grafts to obtain more favorable results. [1][2][3][4][5]8,9,15,22 Autologous fat grafts were combined with numerous different agents in recent years to increase their viability and decrease the rate of resorption including stem cell therapies; growth factors such as platelet-derived growth factor (PDGF), basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF), and epidermal growth factor (EGF); and other agents such as platelet-rich plasma (PRP), activated M2 macrophages, polymer therapy, and matrix metalloproteinase-2. [23][24][25][26][27][28][29][30] All of these agents and modalities demonstrated variable effects on the survival of fat grafts; however, none of them can be considered as the preferred method or agent for this issue.…”

“…Fat grafting is one of the most commonly performed surgical techniques in plastic surgery used both for aesthetic and reconstructive purposes. [1][2][3] The unpredictable resorption rate comes forward as their major drawback which is the main reason creating poor postoperative results. 4,5 Many methods were used earlier to increase fat graft viability including the addition of platelet-rich plasma and even stem cells resulted with variable succeed rates.…”