“…Despite these advantages, a fully operational pCT system does currently not exist, in part, related to the large amount of proton and object data that need to be acquired and reconstructed, respectively. Preliminary work in proton CT over the last several years has centered on the most likely path formalism [8], image reconstruction [6], [3], [4], [5], and basic design of a system [7]. A vital step in the reconstruction of a pCT image is the calculation of the integral relative electron densities, which must be known for each of the proton histories.…”