Reconstruction and Scientific Explanation of Akar Kuning (Arcangelisia flava Merr.) From West Sumatra as Ethnomedicine and Source of Science Learning

Abstract

It is known that the Akar Kuning plant contains various bioactive compounds, one of the most famous being berberine. Akar Kuning are lianas, up to 20 m long, living in lowlands up to 800 m above sea level (asl). The leaves are thick and strong like skin, oval shaped, blunt not sharp, leaf width 7 cm to 20 cm, glossy top surface and long stalk. The flowers are housed in two small sizes arranged in a series of glabrous 20 cm to 50 cm, greenish-white or yellowish-white with buds. 5 The wood is yellow, its purpose is to boil the stems to treat jaundice, digestion, intestinal worms, fever, and canker sores. The fruit, which is yellow in color, can be used to anesthetize fish. 1 This study uses an ethnomedicine approach. Ethnomedicine is the perception and conception ABSTRACT Indonesia is one of the countries that has the largest tropical forest land in the world, this makes Indonesia rich in diversity of flora and fauna. This diversity produces a variety of cultures, traditions and local wisdom. One of the local wisdoms of the people of West Sumatra is the use and utilization of the biodiversity around it as a medicine for various diseases. The type of medicinal plant that is the focus of this research is the type of Akar Kuning plant (Arcangelisia flava Merr.). This research is an educational research conducted using an ethnoscience approach, meaning that it is based on the indigenous knowledge of the local community. This study aims to reconstruct knowledge from a cultural / community perspective in the health sector. which later will become a knowledge with scientific explanation. The data were obtained through direct observation to the research location regarding indigenous knowledge about the Akar Kuning plant and also based on laboratory test data on antibacterial activity carried out in the biology laboratory of Semarang State University. All data obtained will be analyzed and also strengthened by various sources. The analysis concluded that the Akar Kuning (Arcangelisia flava Merr.) Plant contains bioactive compounds that act as antibacterials, thus inhibiting bacterial growth. This is evidenced by the inhibition zone diameter data produced during laboratory tests showing the results that the Yellow Root plant extract (Arcangelisia flava Merr.

Penetapan kadar flavonoid total ekstrak kayu kuning dari daerah Samarkilang Aceh Tengah dengan berbagai konsentrasi etanol menggunakan metode spektrofotometri visible

“…Secara tradisional kayu kuning telah digunakan oleh suku Dayak karena khasiat obatnya, termasuk sebagai antibiotik, analgesik, antipiretik, dan antivirus (Pratama et al, 2018;Pratama, 2017). Tanaman ini mengandung berbagai senyawa bioaktif seperti glikosida, alkaloid (berberine, jatrorhizine, dan palmatine), flavonoid, saponin, dan triterpenoid (Diliarosta et al, 2021;Fatmawati et al, 2022;Wulansari et al, 2014). Senyawa ini berkontribusi terhadap aktivitas farmakologisnya, termasuk efek antimikroba, antioksidan, antiinflamasi, dan kardioprotektif (Ginovyan et al, 2017;Ramadani et al, 2018;Ramadhan et al, 2022;subeki et al, 2005).…”

Bibliometric analysis of local wisdom-based learning: Direction for future history education research

“…Figure 6 shows that there were five authors in red cluster, followed by five authors in green cluster, five authors in blue cluster, three authors in yellow cluster, and two authors in purple cluster. The authors in red cluster simultaneously conducted the research about ethnomedicine-based science learning [22]. Some researches related to local wisdom-based Spermatophyta learning and ethno-science, technology, engineering, and math (STEM)-based science education were carried out by the authors in green cluster and purple cluster [56], [57].…”

Phytochemical Compounds Identification From 70% Ethanol Extract of Arcangelesia Flava (L.) Merr Stems Using LC-MS/MS and In-Silico Molecular Docking Approach as Inhibitor Interleukin-1β

“…Other minor alkaloids include columbamine, dehydrokoridalmin, homoaromolin, and talifendin. 9 The most common bioactive compound is berberine, it is used as an antibacterial treatment by decreasing bacterial protein and cell wall synthesis, 10 an antiinflammatory agent by inhibiting iNOS, 11 an antimalarial agent, 12 and an anticancer agent against MCF-7 (breast adenocarcinoma) and EGFR-2 (HER2-Positive) breast cancer line. 13 Pachybasin also possesses antimicrobial properties.…”