Reconstructie van de schedel van een hond met een titanium mesh na het verwijderen van een multilobulair osteochondrosarcoom

Abstract

An eleven-year-old cavalier King Charles spaniel was presented with a large mass arising from the sagittal crest of the skull. Computed tomography also revealed an intracranial component. A histological diagnosis of multilobular osteochondrosarcoma grade 1 was made from surgical biopsies. Since this tumor type has a moderate aggressive biological behavior characterized by a slow growth, compression of adjacent structures, and only a 30% metastatic rate, surgical resection was performed. A wide partial craniectomy was performed, the skull defect was reconstructed with a designated custom designed titanium mesh and the skin defect closed with a local subdermal plexus flap technique. Histologic evaluation indicated clean surgical margins, which may lead to a long-term survival in this low-grade tumor. Approximately seventeen months after surgical resection, the dog showed no signs of local tumor recurrence or metastasis.

Cranioplasty for Multilobular Osteochondrosarcoma Using 3-Dimensional Printing Technology in Dogs: A Report of Two Cases with a Long-Term Follow-Up

“…Various materials for cranioplasty have been described in dogs, including cortical allografts, polymethyl methacrylate (PMMA), and titanium mesh (7,20,23,27). Cortical allograft bone provides mechanical support; however, it requires aseptic harvesting and preserving techniques (23).…”

“…Although chemotherapy and radiotherapy may have benefits of local control of tumors or palliation of residual tumors (13,30,31), surgery remains the treatment of choice. Clean surgical margins are strongly associated with favorable prognosis (5,7,8,16).…”

Titanium mesh osteosynthesis for the treatment of severely comminuted maxillofacial fractures in four dogs

“…Titanium mesh has been used in dogs for cranioplasty following tumour excision (Bordelon & Rochat 2007, de Casterlé et al 2017. Its biocompatibility, high strength, good malleability, low weight, elastic modulus, immediate availability, minimal inflammatory reaction and minimal imaging artefact (Matthew et al 1996, Bordelon & Rochat 2007, Dewey et al 2007, Boudrieau 2012, Rosselli et al 2017) make titanium an optimal material for maxillofacial reconstruction.…”