Recommended Interventions to Improve Human Papillomavirus Vaccination Uptake among Adolescents: A Review of Quality Improvement Methodologies

Abstract

Background: Routine human papillomavirus (HPV) vaccine uptake continues to be suboptimal since its recommendation in 2006 for girls and in 2011 for boys. This paper aims to review published quality improvement (QI) methodologies on interventions to improve HPV vaccine uptake among adolescents. Methods: Science Direct and Scopus databases were searched for QI initiatives evaluating the effect of multimodal interventions to improve HPV vaccination rates (initiation and/or completion of series) among adolescents. Studies that included an outcome of interest among adolescents aged 10 to 18 years old were included. Two investigators worked independently to screen for potential articles and a designated investigator extracted data on study characteristics and evaluated the outcomes. Results: A preliminary search yielded a total of 523 articles and 13 were included in the final analysis. Common strategies were provider-specific (i.e., webinar, telementoring, train-the-trainer approach) and patient- and/or parent-specific interventions (i.e., reminder emails, phone calls and text messages, social events), with an emphasis on education and knowledge empowerment. System-level interventions such as policy changes and revised protocols were less commonly prescribed despite being associated with a more significant weight on the overall outcome. Conclusions: Creative, sustainable, and economical multilevel interventions that focus not only on provider training and public education but also incorporate local policies and system enhancements can substantially improve HPV vaccination coverage among adolescents.

Effect of an HPV Vaccination Multi-Level, Multi-Component Program on HPV Vaccination Initiation and Completion in a Pediatric Clinic Network

“…Emerging evidence suggests the strength of using multiple intervention strategies through multi-level and multi-component (MLMC) clinic-based intervention approaches to address the complex factors affecting vaccination at the clinic system (organization), provider, and parent levels [29][30][31][32]. Recent studies indicate that implementing these evidence-based interventions concurrently has a synergistic impact on HPV vaccination rates [33][34][35].…”

Avaliação da cobertura vacinal contra HPV em estudantes universitários de Cascavel (Paraná)

“…Admitindo-se que se faz necessária a realização de palestras e divulgação midiática sobre a importância da vacinação como meio de prevenção, informando tanto os adolescentes quanto seus responsáveis, para assim alcançar um maior número de adolescentes imunizados, assim como descrito, também, por Moura et al (2021). Khalid et al (2023), avaliaram as intervenções recomendadas para melhorar a adesão à vacinação contra o papilomavírus humano entre os adolescentes, dentre elas foi verificado que a maioria das intervenções tiveram como centro o avanço do conhecimento dos profissionais de saúde para que possam educar os pacientes e os pais/cuidadores. Sugerindo assim, uma melhoria na comunicação e transmissão das mensagens com confiança aos pacientes, apresentando dados sobre potenciais benefícios da vacinação profilática anti-HPV também devem ser destacadas pelos profissionais de saúde.…”