Recommendations of the Polish Society of Gynaecologists and Obstetricians, Polish Paediatric Society, Polish Society of Family Medicine, Polish Society of Vaccinology, Polish Society of Oncological Gynaecology and Polish Society of Colposcopy and Pathophysiology of the Uterine Cervix on prophylactic vaccinations against infections with human papillomaviruses in Poland

Nowakowski, Andrzej; Jach, Robert; Szenborn, Leszek; Bidziński, Mariusz; Jackowska, Teresa; Kotarski, Jan; Mastalerz-Migas, Agnieszka; Nitsch–Osuch, Aneta; Pinkas, Jarosław; Sawicki, Włodzimierz; Sieroszewski, Piotr; Stukan, Maciej; Wysocki, Jacek

doi:10.5603/gp.a2022.0101

Cited by 2 publications

(2 citation statements)

References 44 publications

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“…In turn, the overexpression and activity of viral oncoproteins E6 and E7 lead to the deregulation of the cell cycle, increased cell division, inhibition of apoptosis, and the accumulation of genetic damage due to inefficient DNA repair, resulting in the development of tumorigenesis [13]. Regular cervical cancer screening, such as Pap smears and HPV testing, is essential for early detection and timely intervention to prevent cervical cancer and its complications [14][15][16]. HPV vaccination is a highly effective preventive measure against HPV infection and its associated diseases, including cervical cancer.…”

Section: Hpv Infection and Cervical Cancermentioning

confidence: 99%

Human Papillomavirus Infections and the Role Played by Cervical and Cervico-Vaginal Microbiota—Evidence from Next-Generation Sequencing Studies

Głowienka-Stodolak,

Bagińska-Drabiuk,

Szubert

et al. 2024

Cancers

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This comprehensive review encompasses studies examining changes in the cervical and cervico-vaginal microbiota (CM and CVM) in relation to human papillomavirus (HPV) using next-generation sequencing (NGS) technology. HPV infection remains a prominent global health concern, with a spectrum of manifestations, from benign lesions to life-threatening cervical cancers. The CM and CVM, a unique collection of microorganisms inhabiting the cervix/vagina, has emerged as a critical player in cervical health. Recent research has indicated that disruptions in the CM and CVM, characterized by a decrease in Lactobacillus and the overgrowth of other bacteria, might increase the risk of HPV persistence and the progression of cervical abnormalities. This alteration in the CM or CVM has been linked to a higher likelihood of HPV infection and cervical dysplasia. NGS technology has revolutionized the study of the cervical microbiome, providing insights into microbial diversity, dynamics, and taxonomic classifications. Bacterial 16S rRNA gene sequencing, has proven invaluable in characterizing the cervical microbiome, shedding light on its role in HPV infections and paving the way for more tailored strategies to combat cervical diseases. NGS-based studies offer personalized insights into an individual’s cervical microbiome. This knowledge holds promise for the development of novel diagnostic tools, targeted therapies, and preventive interventions for cervix-related conditions, including cervical cancer.

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Section: Hpv Infection and Cervical Cancermentioning

confidence: 99%

Human Papillomavirus Infections and the Role Played by Cervical and Cervico-Vaginal Microbiota—Evidence from Next-Generation Sequencing Studies

Głowienka-Stodolak,

Bagińska-Drabiuk,

Szubert

et al. 2024

Cancers

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show abstract

“…High-risk genotypes are typically linked to cervical cancer, vulvar and vaginal cancer, as well as penile, anal, head, and neck cancers. Low-risk genotypes typically result in benign or low-grade cervical lesions, as well as genital warts on various parts of the body, including the cervix, vagina, vulva, penis, scrotum, and anus [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Knowledge of HPV and HPV Vaccination among Polish Students from Medical and Non-Medical Universities

Pruski,

Millert-Kalińska,

Haraj

et al. 2023

Vaccines

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Human papillomavirus (HPV) is a common sexually transmitted infection that can cause both benign and malignant lesions. HPV vaccines, preferably administered before the onset of sexual activity, have demonstrated remarkable efficacy in preventing HPV-related cancers. The impact of a healthcare provider’s recommendation on HPV vaccine acceptance is substantial. Therefore, medical students must undergo thorough training in this domain. This study compares fundamental understanding and viewpoints regarding HPV and anti-HPV vaccines among Polish students pursuing medical and non-medical sciences. This study was based on the authors’ questionnaire, and the results were statistically analyzed. The participants in this study were 1025 students (medical sciences students—520 respondents in total; and non-medical sciences students—505 respondents in total). According to the results, medical students’ knowledge about the consequences of HPV infection and vaccination against HPV was significantly greater. To date, numerous publications have investigated the understanding of particular social, gender, parental, etc., groups about vaccination, but the knowledge of students at different universities—medical and other—has not been compared. Social awareness is still insufficient, even in groups of medical students. There is much to be done to educate and encourage preventive behavior in those not receiving primary prevention in early childhood.

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Abstract: This article has been peer reviewed and published immediately upon acceptance.It is an open access article, which means that it can be downloaded, printed, and distributed freely, provided the work is properly cited. Articles in "Ginekologia Polska" are listed in PubMed.

Cited by 2 publications

References 44 publications

Human Papillomavirus Infections and the Role Played by Cervical and Cervico-Vaginal Microbiota—Evidence from Next-Generation Sequencing Studies

Human Papillomavirus Infections and the Role Played by Cervical and Cervico-Vaginal Microbiota—Evidence from Next-Generation Sequencing Studies

Knowledge of HPV and HPV Vaccination among Polish Students from Medical and Non-Medical Universities

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