Recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 13–15 November 2016

Abstract

; for the ESO-KSU session participants* Abstract About the meeting: The purpose of the European Stroke Organisation (ESO)-Karolinska Stroke Update Conference is to provide updates on recent stroke therapy research and to give an opportunity for the participants to discuss how these results may be implemented into clinical routine. Several scientific sessions discussed in the meeting and each session produced consensus statements. The meeting started 20 years ago as Karolinska Stroke Update, but since 2014, it is a joint conference with ESO. Importantly, it provides a platform for discussion on the ESO guidelines process and on recommendations to the ESO guidelines committee on specific topics. By this, it adds a direct influence from stroke professionals otherwise not involved in committees and work groups on the guidelines procedure. The discussions at the conference may also inspire new guidelines when motivated. The topics raised at the meeting are selected by the scientific programme committee mainly based on recent important scientific publications. The ESO-Karolinska Stroke Update consensus statement and recommendations will be published every 2 years and it will work as implementation of ESO-guidelines Background: This year's ESO-Karolinska Stroke Update Meeting was held in Stockholm on 13-15 November 2016. There were 10 scientific sessions discussed in the meeting and each session produced a consensus statement (Full version with background, issues, conclusions and references are published as web-material and at http://www.eso-karolinska.org/2016 and http://eso-stroke.org) and recommendations which were prepared by a writing committee consisting of session chair(s), secretary and speakers and presented to the 312 participants of the meeting. In the open meeting, general participants commented on the consensus statement and recommendations and the final document were adjusted based on the discussion from the general participants. Recommendations (grade of evidence) were graded according to the 1998 Karolinska Stroke Update meeting with regard to the strength of evidence. Grade A Evidence: Strong support from randomised controlled trials and statistical reviews (at least one randomised controlled trial plus one statistical review). Grade B Evidence: Support from randomised controlled trials and statistical reviews (one randomised controlled trial or one statistical review). Grade C Evidence: No reasonable support from randomised controlled trials, recommendations based on small randomised and/or non-randomised controlled trials evidence.

Aspirin Resistance Affects Medium-Term Recurrent Vascular Events after Cerebrovascular Incidents: A Three-Year Follow-up Study

“…On the basis of the results of our study, we suppose that in many cases of patients with carotid artery stenosis, the regular treatment with ASA at a dose of 150 mg is insufficient. The AHA/ASA and European guidelines for the management of acute stroke did not differentiate the antiplatelet treatment based on the etiology of stroke, and they recommend a dose of 75-320 mg ASA as the drug of first choice regardless of whether the reason of the stroke is small-or large-vessel disease [19,20]. Dual antiplatelet treatment during the first 21 days after a minor stroke or high risk TIA is recommended without any connection with the etiology [21].…”

Цукровий Діабет І Мозковий Інсульт: Сучасний Погляд На Проблему

“…Згідно з європейськими та американськими рекомендаціями щодо інсультів, невідкладна допомога при МІ повинна бути спрямована на стабілізацію життєво важливих функцій, реканалізацію закупорених судин, запобігання ранньому повторному інфаркту, запобігання виникненню або зменшення вторинного ураження нейронів [34,41].…”

En mann i 40-årene med residiverende hjerneinfarkt

“…Persisterende foramen ovale er et vanlig funn og gir ikke økt risiko for hjerneinfarkt (14). Hos pasienter med kryptogene hjerneinfarkter er det likevel vist økt hyppighet hos både yngre og eldre, noe som tyder på at det foreligger en assosiasjon mellom persisterende foramen ovale og hjerneinfarkt (15).…”

“…Det er ikke indisert med forebyggende tiltak eller behandling av asymptomatiske individer der tilstanden blir oppdaget tilfeldig (14). Per i dag anbefales det platehemmende behandling fremfor antikoagulasjonsbehandling som sekundaerprofylakse, såfremt det ikke samtidig foreligger tilstander hvor antikoagulasjonsbehandling er indisert (12).…”

“…European Stroke Organisation anbefalte i 2016 lukking av persisterende foramen ovale ved kryptogent hjerneinfarkt i utvalgte tilfeller hvor den er sannsynlig årsak i henhold til RoPE-skåren (14).…”