1991
DOI: 10.1136/gut.32.7.823
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Recommendations for standards of sedation and patient monitoring during gastrointestinal endoscopy.

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Cited by 138 publications
(55 citation statements)
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“…2.6) [3]. Recent guidelines [25] strongly suggest that the endoscopist should give the opioid drug first, and then slowly give one quarter the dose of benzodiazepine which would have been used as the sole agent. This is based on work showing that with some opioids midazolam exhibits a synergistic sedative effect [26,27], while with others the effect is at least additive [28].…”
Section: Discussionmentioning
confidence: 99%
“…2.6) [3]. Recent guidelines [25] strongly suggest that the endoscopist should give the opioid drug first, and then slowly give one quarter the dose of benzodiazepine which would have been used as the sole agent. This is based on work showing that with some opioids midazolam exhibits a synergistic sedative effect [26,27], while with others the effect is at least additive [28].…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, to control sedation with propofol it is essential that a person other than the one carrying out the endoscopy be present (9). For these reasons, the introduction of propofol as a substitute for benzodiazepines and opiates in endoscopy could justify an incorporation of anesthetists into these units.…”
mentioning
confidence: 99%
“…On the other hand, there are efficient antagonists such as flumazenil and naloxone that must be part of the stocks at every endoscopy unit. On other occasions, the presence of risk criteria related to sedation may determine the presence of an anesthetist (9,10).…”
mentioning
confidence: 99%
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