Recommendations and unanswered questions in the diagnosis and treatment of thyroid nodules

Paschke, Ralf; Reiners, C.; Führer, Dagmar; Schmid, Kurt Werner; Dralle, Henning; Brabant, G

doi:10.1055/s-2005-871906

Cited by 19 publications

(24 citation statements)

References 14 publications

(21 reference statements)

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“…However, several questionnaire studies with European, North American, and Australian endocrinologists repeatedly revealed large discrepancies in the diagnosis and management of thyroid nodules (23)(24)(25)(26). Among other discrepancies, a less frequent application of the fine needle aspiration biopsy (FNAB), more frequent use of thyroid scintigraphy, thyroid US calcitonin (CT), and thyroid peroxidase (TPO) antibody determination for the diagnosis of thyroid nodules in Europe as compared with North America and different strategies for the treatment of thyroid nodules became apparent.…”

Section: Epidemiology and Risks Of Benign And Malignant Thyroid Diseasesmentioning

confidence: 99%

Thyroid nodules: a review of current guidelines, practices, and prospects

Gharib

Papini

Paschke

2008

European Journal of Endocrinology

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129

101

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In 2006, two major society-sponsored guidelines and one major consensus statement for thyroid diagnosis and management were published by: the American Association of Clinical Endocrinologists/Associazione Medici Endocrinologi (AACE/AME); the American Thyroid Association (ATA); and the European Thyroid Association (ETA). A careful review of these guidelines reveals that despite many similarities, significant differences are also present, likely reflecting differences in practice patterns, interpretation of existing data, and availability of resources in different regions. The methodology of the guidelines is similar, but a few differences in the rating scale make a rapid comparison of the strength of both evidence and recommendations difficult for the use in current clinical practice. Some recommendations are based mostly on experts' opinion. Thus, a same recommendation may be based on a different evidence; on the other hand, sometimes the same evidence may induce a different recommendation. Therefore, efforts are needed to produce a few high-quality clinical studies to close the evidence gaps in the still controversial fields of thyroid disease and to create a joint task force of the most authoritative societies in the field of thyroid disease in order to reach a common document for clinical practice recommendations. European Journal of Endocrinology 159 493-505

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Section: Epidemiology and Risks Of Benign And Malignant Thyroid Diseasesmentioning

confidence: 99%

Thyroid nodules: a review of current guidelines, practices, and prospects

Gharib

Papini

Paschke

2008

European Journal of Endocrinology

Self Cite

129

101

View full text Add to dashboard Cite

show abstract

“…Vorliegen einer SD-Autonomie und 2. Vorliegen eines malignen Prozesses [1,3,[5][6][7][8]. Des Weiteren kann eine mechanische Beeinträchtigung (Trachea-und/oder Ösophaguskompression), insbesondere bei Vorliegen multinodöser Strumen, von klinischer Bedeutung sein [6,9].…”

Section: Dignität Und Aktivität -Zwei Entscheidende Fragenunclassified

“…Nach älteren internationalen Erhebungen liegt die Karzinomprävalenz in SD-Knoten bei etwa 3-5% [10,11]. Die Daten deutscher Krebsregister zeigen hingegen eine wesentlich niedrigere Karzinomprävalenz von etwa 0,1% [1]. 4.…”

Section: Dignität Und Aktivität -Zwei Entscheidende Fragenunclassified

“…Thyreoglobulin: Die Bestimmung von Serumthyreoglobulin zur Differentialdiagnostik nodulärer SD-Veränderungen ist nicht indiziert [1,2,5].…”

Section: Dignität Und Aktivität -Zwei Entscheidende Fragenunclassified

“…Es ist daher ein Anliegen dieser Veröffentlichung, dem Leser unter Einbeziehung aktueller Stellungnahmen und Empfehlungen, u.a. der Sektion Schilddrüse der Deutschen Gesellschaft für Endokrinologie (DGE), der European Thyroid Association (ETA) und der American Thyroid Association (ATA) [1][2][3][4][5], eine rationale und rationelle Herangehensweise an die Diagnostik von SD-Knoten darzustellen. Zudem erfolgt eine kritische Auseinandersetzung mit den Vor-und Nachteilen der national wie international unterschiedlich praktizierten Standards zur Abklärung von SD-Knoten.…”

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