Recomendaciones sobre el uso de metotrexato en pacientes con artritis psoriásica

Cañete, Juan D.; Ariza‐Ariza, Rafael; Bustabad, Sagrario; Delgado, C Romero; Fernández‐Carballido, Cristina; Llorente, J. F. Garcia; Loza, Estíbaliz; Montilla, Carlos; Naranjo, Antonio; Pinto, José Antônio; Queiró, Rubén; Ramírez, Julio; Tornero-Molina, Jesús

doi:10.1016/j.reuma.2017.08.011

Cited by 6 publications

(1 citation statement)

References 47 publications

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“…Overall, the pharmacological therapeutic options are often inadequate; the lack of disease-modifying drugs lead a considerable amount of patients to face destructive lesions and consequent high functional impairment. On the other hand, there are several synovitis PsA treatment options, including disease-modifying antirheumatic drugs (DMARDs); among them Methotrexate has been identified as the drug of choice [53,54] by EULAR and GRAPPA recommendations.…”

Section: Lack Of Evidence For Effective Systemic Therapy In Ehoamentioning

confidence: 99%

Hand Erosive Osteoarthritis and Distal Interphalangeal Involvement in Psoriatic Arthritis: The Place of Conservative Therapy

Poletto

Tinazzi

Marchetta

et al. 2021

JCM

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Hand erosive osteoarthritis (HEOA) and Psoriatic Arthritis (PsA) with DIP involvement are common diseases affecting the hand. Both of them evolve with a progressive limitation in grip due to limited range of motion of the affected joints and stenosing tenosynovitis. Pharmacological options currently available (corticosteroids and clodronate or Idrossicloroquine) for the treatment of EHOA are mostly symptomatic and currently there are no effective drugs able to modify the course of the disease. In addition, data on drug effectiveness of PsA with DIP involvement are lacking. Conservative therapy should be considered in order to reduce pain and improve hand functionality. There are many studies debating a wide range of non-pharmacological intervention in the management of HEOA: joint protection program, range of motion and strengthening exercise, hand exercise with electromagnetic therapy, application of heat with paraffin wax or balneotherapy, occupational therapy and education. Concerning conservative treatment strategies to treat PsA, on the contrary, current evidence is still weak. Further research is needed to find the correct place of physical therapy to prevent stiffness and ankylosis due to the vicious circle of inflammation-pain-immobility-rigidity.

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Section: Lack Of Evidence For Effective Systemic Therapy In Ehoamentioning

confidence: 99%