Recomendaciones 2013 para el uso de la monitorización ambulatoria de la presión arterial para el diagnóstico de hipertensión en adultos, valoración de riesgo cardiovascular y obtención de objetivos terapéuticos (resumen). Recomendaciones conjuntas de la International Society for Chronobiology (ISC), American Association of Medical Chronobiology and Chronotherapeutics (AAMCC), Sociedad Española de Cronobiología Aplicada, Cronoterapia y Riesgo Vascular (SECAC), Sociedad Española de Arteriosclerosis (SEA) y R

Hermida, Ramón C.; Smolensky, Michael H.; Ayala, Diana E.; Portaluppi, Francesco; Crespo, Juan J.; Fabbian, Fabio; Haus, Erhard; Manfredini, Roberto; Mojón, Artemio; Moyá, Ana; Piñeiro, Luis González; Ríos, María T; Otero, Alfonso; Bălan, Horia; Fernández, José R.

doi:10.1016/j.arteri.2013.03.002

Cited by 29 publications

(5 citation statements)

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“…DAYLIGHT is the largest prospective, double-blind, randomized, and controlled trial study designed to examine the influence of vitamin D on BP [ 21 ]. Briefly, 534 individuals (36 ± 10 yr) with untreated, elevated BP (131 ± 10 mmHg) and vitamin D deficiency (15 ± 6.3 ng/mL) were randomized to 6 months of low-dose (400 IU/d) or high-dose (4000 IU/d) vitamin D. The primary endpoint of DAYLIGHT was 24 hr BP, the gold standard of BP assessment [ 22 ]. Body Mass Index (BMI), season, sunlight exposure, alcohol intake, and smoking status were also collected as they may influence the effect of vitamin D on vascular function and BP changes from baseline.…”

Section: Methodsmentioning

confidence: 99%

High-Dose versus Low-Dose Vitamin D Supplementation and Arterial Stiffness among Individuals with Prehypertension and Vitamin D Deficiency

et al. 2015

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Introduction. Vitamin D deficiency is associated with the onset and progression of hypertension and cardiovascular disease (CVD). However, mechanisms underlying vitamin D deficiency-mediated increased risk of CVD remain unknown. We sought to examine the differential effect of high-dose versus low-dose vitamin D supplementation on markers of arterial stiffness among ~40 vitamin D deficient adults with prehypertension. Methods. Participants were randomized to high-dose (4000 IU/d) versus low-dose (400 IU/d) oral vitamin D3 for 6 months. 24 hr ambulatory blood pressure (BP), carotid-femoral pulse wave velocity, and pulse wave analyses were obtained at baseline and after 6 months of vitamin D supplementation. Results. There were no changes in resting BP or pulse wave velocity over 6 mo regardless of vitamin D dose (all p > 0.202). High-dose vitamin D decreased augmentation index and pressure by 12.3 ± 5.3% (p = 0.047) and 4.0 ± 1.5 mmHg (p = 0.02), respectively. However, these decreases in arterial stiffness were not associated with increases in serum 25-hydroxyvitamin D over 6 mo (p = 0.425). Conclusion. High-dose vitamin D supplementation appears to lower surrogate measures of arterial stiffness but not indices of central pulse wave velocity. Clinical Trial Registration. This trial is registered with www.clinicaltrials.gov (Unique Identifier: NCT01240512).

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Section: Methodsmentioning

confidence: 99%

High-Dose versus Low-Dose Vitamin D Supplementation and Arterial Stiffness among Individuals with Prehypertension and Vitamin D Deficiency

et al. 2015

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“…In a retrospective study, at a mean age of 52 years, nighttime mean systolic BP was the most significant predictor of cardiac events [6]. Although the sample was small, our results indicate that subjects with severe ROP need early follow-up for BP control and, if required, treatment.…”

Section: Discussionmentioning

confidence: 93%

“…Hypertension was defined as the mean systolic daily ambulatory BP >135 mm Hg and/or under BP medication or a mean systolic nighttime BP >120 mm Hg [6]. Diastolic hypertension was defined as daily ambulatory BP >85 mm Hg [6].…”

Section: Methodsmentioning

confidence: 99%

Retinopathy of Prematurity Is Associated with Increased Systolic Blood Pressure in Adults Who Were Born Preterm

Kistner

Jacobson²,

Östergren³

et al. 2017

Neonatology

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Background: Adults born preterm are at risk of developing cardiovascular morbidities. Objective: The aim of this study was to evaluate the relationship between retinopathy of prematurity (ROP) and blood pressure (BP) and salivary cortisol levels during adulthood. Methods: Sixty-nine subjects (mean age 22.6 years) were included. Subjects were adults who were: (a) ex-preterm infants with severe ROP (n = 22), born at gestational age (GA) <30 weeks with a birth weight (BW) <1,000 g, (b) ex-preterm infants with no/mild ROP (n = 21), born at GA <28 weeks with a BW <1,000 g, or (c) full-term controls (n = 26). Anthropometric data, office BP, ambulatory BP, and morning and evening salivary cortisol were analyzed. Results: As adults, ex-preterm infants with severe ROP had on average 7.4 mm Hg higher systolic office BP than those with no/mild ROP (p = 0.019) and controls (p = 0.007). A high cortisol level, tall height, and severe ROP were independent predictors of higher ambulatory systolic BP during adulthood in forward stepwise regression analysis, independent of GA. Conclusion: Our results indicate that preterm infants with severe abnormal retinal vascular development during the neonatal period may be at an increased risk for increased BP during adulthood. We found no differences between those with no/mild ROP as infants and controls with regard to BP data.

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“…Analyzing the dipper pattern, we found that the normal BP T2DM had the lowest percentage of dipper pattern among the study groups, although all BP values were within normal range. A possible explanation for the higher prevalence of dipper pattern in the HTN groups compared to the normal BP group might relay in the beneficial effect of HTN treatment on nocturnal BP fall (29). The authors previously demonstrated that ingestion of at least one HTN medication at bedtime positively influenced the dipper pattern in T2DM and control subjects (30).…”

Section: Discussionmentioning

confidence: 97%

High-sensitivity C-reactive protein is associated with 24-hour ambulatory blood pressure variability in type 2 diabetes and control subjects

Ciobanu

Bala

Vereşiu

et al. 2016

Revista Romana De Medicina De Laborator

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Background and Aim: Type 2 diabetes (T2DM) has been associated with hypertension (HTN) and elevated high-sensitivity C-reactive protein (hsCRP), but the possible implication of blood pressure (BP) variability in increasing hsCRP in T2DM are incompletely understood. We aimed to assess the association between hsCRP and BP variability during 24-hour ambulatory BP monitoring in T2DM and healthy control subjects. Material and Method: The cross-sectional study included data from T2DM patients with normal BP (n=9), controlled HTN (n=46), uncontrolled HTN (n=20), and healthy controls (n=11). HsCRP was assessed using ELISA technique. All subjects underwent 24-hour ambulatory BP monitoring; BP variability was calculated using standard deviation. Results: We found that hsCRP was associated with daytime and 24-hours systolic and diastolic BP variability. Higher hsCRP were observed in T2DM patients with uncontrolled HTN and high BP variability compared to the other three groups. In multiple regression analysis, hsCRP was predicted by daytime and 24-hour diastolic BP variability. Conclusions: Our findings suggest that high hsCRP was associated with increased ambulatory BP variability in T2DM and control subjects. The contribution of both hsCRP and BP variability to cardiovascular risk stratification in T2DM needs to be evaluated in prospective studies.

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Cited by 29 publications

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High-Dose versus Low-Dose Vitamin D Supplementation and Arterial Stiffness among Individuals with Prehypertension and Vitamin D Deficiency

High-Dose versus Low-Dose Vitamin D Supplementation and Arterial Stiffness among Individuals with Prehypertension and Vitamin D Deficiency

Retinopathy of Prematurity Is Associated with Increased Systolic Blood Pressure in Adults Who Were Born Preterm

High-sensitivity C-reactive protein is associated with 24-hour ambulatory blood pressure variability in type 2 diabetes and control subjects

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