Recombination and chromosome structure in eukaryotes

Abstract

Allelic recombination frequency and pattern in fungi show strong gene-to-gene variation. At least in two fungal species, Neurospora and Schizophyllum, recombination frequencies in certain chromosomal segments are genetically determined. The possibility that chromosomal proteins and/or synaptinemal complexes may play an important role in regulation of recombination frequency and pattern is discussed.

Primer on Medical Genomics Part II: Background Principles and Methods in Molecular Genetics

“…23 However, the chance of segregating together is not 100% because of the "phenomenon" (process) of recombination (crossing over). [252][253][254][255][256] During recombination, the naturally occurring exchange of chromosome regions between ho-mologous pairs of chromosomes happens during meiosis. 257 The chance for a recombination event to occur depends on the distance between the 2 genes on the same chromosome.…”