Recombinant human collagen digestates exhibit higher protective effect on UVA-damaged skin fibroblasts than animal-derived collagens

Wang, Lin; Li, Jia; Zhang, Yue; Zhu, Zhiling; Gao, Ruichang

doi:10.1016/j.jff.2024.106035

Cited by 1 publication

(1 citation statement)

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“…UVA rays, characterize by longer wavelengths, possess the remarkable capability to penetrate deep into the dermis, the skin's thickest layer, thereby inducing oxidative stress and accelerating photoaging [21]. Conversely, UVB rays, while not penetrating the skin as deeply as UVA rays, primarily contribute to sunburn and can instigate the onset of skin cancer [20].…”

Section: Ultraviolet Radiation and Photoprotectionmentioning

confidence: 99%

Beyond Traditional Sunscreens: A Review of Liposomal-Based Systems for Photoprotection

Miranda,

Cruz,

Girão

et al. 2024

Pharmaceutics

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Sunscreen products are essential for shielding the skin from ultraviolet (UV) radiation, a leading cause of skin cancer. While existing products serve this purpose, there is a growing need to enhance their efficacy while minimizing potential systemic absorption of UV filters and associated toxicological risks. Liposomal-based formulations have emerged as a promising approach to address these challenges and develop advanced photoprotective products. These vesicular systems offer versatility in carrying both hydrophilic and lipophilic UV filters, enabling the creation of broad-spectrum sunscreens. Moreover, their composition based on phospholipids, resembling that of the stratum corneum, facilitates adherence to the skin’s surface layers, thereby improving photoprotective efficacy. The research discussed in this review underscores the significant advantages of liposomes in photoprotection, including their ability to limit the systemic absorption of UV filters, enhance formulation stability, and augment photoprotective effects. However, despite these benefits, there remains a notable gap between the potential of liposomal systems and their utilization in sunscreen development. Consequently, this review emphasizes the importance of leveraging liposomes and related vesicular systems as innovative tools for crafting novel and more efficient photoprotective formulations.

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Section: Ultraviolet Radiation and Photoprotectionmentioning

confidence: 99%