Recognition and imitation of pantomimed motor acts after unilateral parietal and premotor lesions: a perspective on apraxia

Halsband, Ulrike; Schmitt, J. Eric; Weyers, Mh.; Binkofski, Ferdinand; G, Grützner; Freund, Hans‐Joachim

doi:10.1016/s0028-3932(00)00088-9

Cited by 136 publications

(106 citation statements)

References 45 publications

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“…Mental imagery of hand and finger movements was found to be impaired in patients with unilateral parietal lesions, who had difficulties in producing movements with their hands and fingers (Sirigu et al 1996). It has been reported that patients with unilateral parietal lesions have more difficulty in imitating gestures involving their own bodies relative to movements involving external objects, particularly if the lesion is in the left hemisphere (Halsband et al 2001).…”

Section: Biological Motion Perception Versus Human Motion Perceptionmentioning

confidence: 98%

Electrophysiology and brain imaging of biological motion

Puce

Perrett

2003

Phil. Trans. R. Soc. Lond. B

626

460

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The movements of the faces and bodies of other conspecifics provide stimuli of considerable interest to the social primate. Studies of single cells, field potential recordings and functional neuroimaging data indicate that specialized visual mechanisms exist in the superior temporal sulcus (STS) of both human and non-human primates that produce selective neural responses to moving natural images of faces and bodies. STS mechanisms also process simplified displays of biological motion involving point lights marking the limb articulations of animate bodies and geometrical shapes whose motion simulates purposeful behaviour. Facial movements such as deviations in eye gaze, important for gauging an individual's social attention, and mouth movements, indicative of potential utterances, generate particularly robust neural responses that differentiate between movement types. Collectively such visual processing can enable the decoding of complex social signals and through its outputs to limbic, frontal and parietal systems the STS may play a part in enabling appropriate affective responses and social behaviour.

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Section: Biological Motion Perception Versus Human Motion Perceptionmentioning

confidence: 98%

Electrophysiology and brain imaging of biological motion

Puce

Perrett

2003

Phil. Trans. R. Soc. Lond. B

626

460

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“…The apraxia after left parietal damage is often present when using either hand (Alexander et al, 1992;Haaland and Harrington, 1996;Leiguarda and Marsden, 2000;Halsband et al, 2001). Additionally, our results seem to be consistent with a meta-analysis of parietal activation studies (Nickel and Seitz, 2005), which suggests that the left IPL is involved in the handobject interaction, and with Heilman et al (1982), who, based on an analysis of human lesion data, suggested that the inferior parietal lobule (supramarginal gyrus) contains visuokinesthetic representations (i.e., perceptual representations related to the motor performances with objects and tools).…”

Section: Dominance Of the Left Hemisphere For The Sensation Of Hand-omentioning

confidence: 99%

Somatic Sensation of Hand-Object Interactive Movement Is Associated with Activity in the Left Inferior Parietal Cortex

Naito¹,

Ehrsson²

2006

J. Neurosci.

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Manipulation of objects and tool-use are known to be controlled by a network of frontal motor and parietal areas. Here, we investigate which of these areas are associated with the somatic sensation of hand-object interactive movement using functional magnetic resonance imaging.To dissociate the sensation of movement from the motor control commands, we used a new kinesthetic illusion. Twelve blindfolded right-handed participants placed the palm of their right or left hand on an object (a ball). Simultaneously, we vibrated the tendon of the wrist extensor muscle. This elicited the illusion that the wrist is flexing and the touched object is also moving along with the hand (hand-object illusion). As controls, we vibrated the skin surface over the nearby bone, which does not elicit any illusions, or we vibrated the tendon when the hand did not touch the object, which only generates the illusory flexion of the hand.We found that the hand-object illusion specifically activated the left inferior parietal lobule (IPL) (supramarginal gyrus and parietal operculum, including cytoarchitectonic areas ip1 and op1) and area 44. The left IPL was activated both during the hand-object illusions with the right and left hands, and the activity was greater than in the right corresponding parietal region, suggesting a dominant role of the left hemisphere.We conclude that the left IPL is involved in the somatic perception of hand-object interactive movement and suggest that the underlying mechanism is the somatic integration of internal information about the body and external information about the object.

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“…In right-handed individuals, patients with apraxia are likely to have left hemisphere damage {Heilman, Maher, Greenwald 1997}, particularly in the parietal lobe, but cases have been described with lesions in the premotor cortex bilaterally or lesions in the non-dominant parietal cortex (Halsband et al, 2001). There is currently no unifying explanatory framework for apraxic phenomena, which is perhaps not surprising given the multiplicity of parietal functions in motor control (Culham and Valyear, 2006;Fogassi and Luppino, 2005).…”

Section: Apraxia and The Case Of Patient Bgmentioning

confidence: 99%

Towards a computational neuropsychology of action

Krakauer

Shadmehr

2007

Progress in Brain Research

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From a computational perspective, the act of using a tool and making a movement involves solving three kinds of problems: we need to learn the costs that are associated with our actions as well as the rewards that we may experience at various sensory states. We need to learn how our motor commands produce changes in things that we can sense. Finally, we must learn how to actually produce the motor commands that are needed so that we minimize the costs and maximize the rewards. The various computational problems appear to require different kinds of error signals that guide their learning, and might rely on different kinds of contextual cues that allow their recall. Indeed, there may be different neural structures that compute these functions. Here we use this computational framework to review the motor control capabilities of two important patients: HM, who suffered from severe amnesia, and BG, who suffered from apraxia. When viewed from a computational perspective, the capabilities and deficits of these patients provide insights into the neural basis of our ability to willfully move our limbs and interact with the objects around us.

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Recognition and imitation of pantomimed motor acts after unilateral parietal and premotor lesions: a perspective on apraxia

Cited by 136 publications

References 45 publications

Electrophysiology and brain imaging of biological motion

Electrophysiology and brain imaging of biological motion

Somatic Sensation of Hand-Object Interactive Movement Is Associated with Activity in the Left Inferior Parietal Cortex

Towards a computational neuropsychology of action

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