Dehydration of the tissues with acetone is one of the critical phases of the plastination procedure, and much acetone is utilized in this step—the present study aimed at acetone reclamation with essential laboratory equipment cost-effectively. The objective was to use the reclamated acetone and not discard it in the environment. In this experiment, 150 liters of impure (used) acetone was taken for reclamation through a simple distillation method. The Institutional Ethical Committee (IEC) of Symbiosis Medical College for Women, Pune, approved the study. Essential laboratory equipment included two heat-resistant glass jars with stoppers, ½ a diameter stainless steel tube, a cooling chamber, a thermostat-controlled hot water bath, an electrode pH meter, and a laboratory thermometer. The cooling chamber condensed the boiling acetone vapours, and pure acetone was collected in the glass jar. The results were calculated using descriptive statistics. With this acetone reclamation setup, 150 liters of impure acetone were recycled, and 128 liters of acetone with a purity of 97% - 99.3% was recovered. The essential equipment for this study pre-existed in our laboratory. The current study also proposes installing a cost-effective acetone reclamation unit at plastination labs to avoid disposing of the impure acetone as toxic waste, thus preventing it from harming the environment. KEYWORDS: Acetone recycling, acetone reclamation, chemical hazards, cost-effective plastination.