Recipient selection, timing of referral, and listing for lung transplantation

Abstract

Recipient selection for lung transplantation is a balance between providing access to transplantation to maximum patients, while utilizing this limited resource in the most optimal way. This review summarizes the current literature and recommendations about referral, listing, and evaluation of lung transplant candidates, with a focus on patients considered to have high risk characteristics.

Utility and safety of airway stenting in airway stenosis after lung transplant: A systematic review

“…This might be partly explained by the heterogeneity between two studies. We noticed an obvious difference in the population between the two studies (21,32). DiBardino et al (7) conducted their study among patients who were stented or non-stented.…”

“…When comparing patients stented and never stented ( 7 ) and pre- and post-stent ( 19 ), lung function returned to baseline after 12 months ( 19 ), or only in patients who ultimately were able to undergo stent removal could improvement be observed ( 20 ). The limited sample size might be part of the reason because the referred studies were retrospective studies with sample sizes of 4 ( 32 ), 20 ( 20 ), and 25 ( 19 ) respectively. In addition, most studies (12/17) lacked a control group.…”

Multidisciplinary team discussion: the emerging gold standard for management of cardiopulmonary complications of connective tissue disease

“…In CTEPH, rates of RHC and pulmonary endarterectomy were significantly increased following multidisciplinary implementation, 44 indicating improved adherence with best‐practice guidelines. It is also likely that an understanding of disease complexity and the limitations of available therapies may increase timely referral for lung transplantation, a treatment shown to increase survival in ILD 45 …”

“…It is also likely that an understanding of disease complexity and the limitations of available therapies may increase timely referral for lung transplantation, a treatment shown to increase survival in ILD. 45 …”

Extracorporeal Membrane Oxygenation for Lung Transplantation

“…8 More than the type of ECMO (VA or VV ECMO), it is the timing of the initiation of ECMO, after transplantation, that remains the most important predictor of the ECMO for PGD post lung transplant outcomes. Lung protective ventilation and peripheral cannulation of VV ECMO initiation, at the time of lung transplantation, have been reported by most authors, 9 who prefer to withhold anticoagulation at ECMO initiation, until adequate hemostasis of lung transplantation is achieved. In addition, recipient coagulopathy should be urgently corrected before initiating ECMO for lung transplant.…”