Recherche des antigènes HL-A dans la maladie de Behçet

HLA and keratoconus

“…Ohno et al (1975) have reported an increased frequency of B5 in Japanese patients with Behcet's disease, a finding which they further extended (Ohno et al 1978) and concluded that HLA-B5 was most commonly found among males with a complete form of the Behcet's disease. An increase of HLA-BS was also reported in European Caucasoids with Behcet's disease (Rosselet et al 1976, Bloch-Michel et al 1979). Behcet's disease is a systemic disease associated with several immunological changes including the prescence of immune complexes in patients' sera (Rahi et al 1979).…”

Familial cases of Behcet's disease

“…Some races are particularly prone to Behcet's disease; most cases come from Turkey and Japan. HLA-B5 tissue type has been found to be predominant in patients with this disease (Lehner, 1967;Ohno et al, 1975;Firat et al, 1976;Rosselet, Saudan & Jeannet, 1976;Dundar & Ozerkan, 1980). More than one case of Behcet's disease in the same family is rarely reported in the literature (Dundar, 1979;Yurutken, Yilmazer & Ozkarakas, 1979).…”