Recent trends in the prevalence of Helicobacter Pylori in symptomatic children: A 12-year retrospective study in a tertiary centre

Tang, Michelle Yeuk‐Lam; Chung, Patrick Ho Yu; Chan, Hau Yee; Tam, Paul Kwong Hang; Wong, Kenneth K. Y.

doi:10.1016/j.jpedsurg.2018.10.079

Cited by 26 publications

(24 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…13 In Sari, Northern Iran, a cross-sectional seroprevalence study revealed 44.5% seropositivity (41.3% in urban and 47.8% in rural areas, with no significant difference between genders), which was significantly higher (66.2%) 15 years before in the same population. Based on the interview and demographic data, seropositivity was higher in men, and it increased with age, BMI, and number of siblings; seropositivity decreased with education and socioeconomic family level at birth.…”

Section: Other Prevalence Studies In the General Populationmentioning

confidence: 94%

“…The infection rate significantly (P = .003) decreased from 25.6% to 12.8% within this period. 13 In Sari, Northern Iran, a cross-sectional seroprevalence study revealed 44.5% seropositivity (41.3% in urban and 47.8% in rural areas, with no significant difference between genders), which was significantly higher (66.2%) 15 years before in the same population. 14 In Austria, the H pylori and CagA status was assessed for a 25-year period in duodenal ulcer and gastric cancer patients in a large tertiary reference center.…”

Section: Changing Prevalencementioning

confidence: 94%

See 1 more Smart Citation

Review: Epidemiology of Helicobacter pylori infection

et al. 2019

View full text Add to dashboard Cite

This review summarizes recent publications on the epidemiology of Helicobacter pylori. Two major systemic analyses, from Malaysia and Ethiopia, were published. The Brazilian Consensus Conference has stated that H pylori infection is an infectious disease with an indication for antimicrobial therapy. A continuous decrease in H pylori prevalence was reported from many regions worldwide, including Korea, China, Iran, and Austria. A cross‐sectional H pylori prevalence study conducted in the United Arab Emirates found 41% prevalence in a group of healthy children and adults. Several studies from Asia addressed H pylori prevalence in adults undergoing regular checkup. The largest of such studies, performed in Korea, involved 24 471 subjects and reported 41.5% seroprevalence. A relatively smaller study from East China on 3252 subjects reported 27.5% prevalence. In contrast, a study from Spain reported 87.2% seroprevalence. A report on the association between smoking and H pylori seropositivity was published on behalf of the Stomach Cancer Pooling (StoP) Project—a consortium of epidemiological studies of gastric cancer. Also, other potential risk factors, including occupational risk factors, water supply, and food were analyzed. Gastroesophageal reflux and sexual partners has been associated with a higher risk for H pylori acquisition, and gut microbiota was suggested to play a role in intrafamilial transmission of H pylori. Finally, in a few studies (from Mexico and Japan), the catalytic model for predicting the potential risk of acquiring H pylori infection in the future was used. As anticipated, a further decline in H pylori‐related disease was demonstrated by applying the modeling.

show abstract

Section: Other Prevalence Studies In the General Populationmentioning

confidence: 94%

Section: Changing Prevalencementioning

confidence: 94%

Review: Epidemiology of Helicobacter pylori infection

et al. 2019

View full text Add to dashboard Cite

show abstract

“…The epidemiology of H pylori is rapidly changing, as shown by the high number of epidemiologic studies published in the last year. The world prevalence of H pylori varies significantly, from 2.5% in Japan to 34.6% in Ethiopia (Table ). Nonetheless, a decreasing trend in the prevalence of H pylori infection among children is being observed.…”

Section: Epidemiologymentioning

confidence: 99%

“…Nonetheless, a decreasing trend in the prevalence of H pylori infection among children is being observed. Tang et al reported a statistically significant decrease in the H pylori infection rate in symptomatic children between 2005 (25.6%) and 2017 (12.8%) in China. However, infection rates remain higher in some groups of children, dependent on factors such as low socioeconomic status and bad sanitary conditions as was concluded in studies from Poland, Peru, China, and Ethiopia …”

Section: Epidemiologymentioning

confidence: 99%

See 1 more Smart Citation

Review: Helicobacter pylori in pediatrics

2019

View full text Add to dashboard Cite

Despite a decrease in the prevalence of Helicobacter pylori infection, it still poses a significant health burden worldwide. This review summarizes important pediatric studies on H pylori published from April 2018 to March 2019. Epidemiologic studies have reported different prevalences in different parts of the world and have mainly confirmed traditional risk factors. Several studies on pathophysiology attempted to identify risk markers in childhood for gastric cancer development later in life. One of the most interesting studies evaluated the relationship between eosinophilic esophagitis and H pylori infection; however, an inverse relationship was not confirmed. The high resistance of H pylori and, consequently, low eradication rates, is still a major concern and susceptibility testing before treatment has again been highlighted. Potassium‐competitive acid blockers are promising new acid‐suppressant drugs but their role in H pylori eradication schemes is still to be determined.

show abstract

The impacts of probiotics in eradication therapy of Helicobacter pylori

Bai

Zhu

et al. 2022

Arch Microbiol

View full text Add to dashboard Cite

Helicobacter pylori (H. pylori) is a well-known pathogen that infects approximately half of the world’s population. It is a pathogenic agent with potential health hazards related to diverse diseases, especially digestive diseases, such as chronic gastritis, peptic ulcer, and gastric carcinoma. In clinical, antibiotics are commonly applied in eradication therapy of H. pylori. However, the increase in antibiotic resistance and side effects has induced the failure of eradication therapy. Recent studies have shown that probiotic supplementation has promising application prospects. It can restore the gastrointestinal microbiota balance and prevent dysbacteriosis caused by antibiotics. Furthermore, it has been reported to have direct or indirect inhibitory effects on H. pylori. Probiotics may have a beneficial effect on H. pylori eradication. However, the strain, dosages, duration times, and safety of probiotic supplementation need further study before clinical applications.

show abstract

Recent trends in the prevalence of Helicobacter Pylori in symptomatic children: A 12-year retrospective study in a tertiary centre

Cited by 26 publications

References 20 publications

Review: Epidemiology of Helicobacter pylori infection

Review: Epidemiology of Helicobacter pylori infection

Review: Helicobacter pylori in pediatrics

The impacts of probiotics in eradication therapy of Helicobacter pylori

Contact Info

Product

Resources

About