Recent trends in synthetic strategies using magnetic nanostructures as green catalysts in synthesis of pyran analogues

Abstract

In recent years, magnetic nanoparticles and nanocomposites play an important role as a nanocatalyst in the creation of a wide range of bioactive heterocycles with extraordinarily high activity and selectivity, low energy consumption, and extended life. Among all heterocycles, many natural products, pharmaceuticals, and bioactive compounds contain pyran scaffolds which have a wide range of uses in biomedical research, industry, and medicine. Additionally, these are also widely used in the synthesis of novel heterocyclic systems as precursors. This study focused on recent advances in the last 5 years in using various magnetic recoverable and recycled nanoparticles and nanocomposites to synthesize pyran derivatives and their pharmacological activity. This article has been classified into three subsections: (i) MNPs‐metal nanocomposite catalyzed reactions, (ii) MNPs‐organic based nanocomposite catalyzed reactions, and (iii) MNPs‐ionic liquid nanocomposite catalyzed reactions and (iv) MNPs‐acid based nanocomposite to describe catalytic efficiency of magnetic nanocomposites for the synthesis of pyran derivatives. A comparative study of nanocomposites and different approaches for green synthesis of pyrans by highlighting the advantages and disadvantages along with catalyst recovery and recyclability has been mentioned, which will help scientists to probe and stimulate the study of these scaffolds.

Oxygen vacancy enhanced catalytic activity in a Pt nanoparticle decorated GO–CexOycatalyst for the efficient synthesis of pyran based derivatives

“…Pyran and its derivatives have received much attention from synthetic and pharmaceutical chemists because of their incredible chemical and pharmaceutical properties. 27,28 The structural moiety of the pyran structure possesses various biological properties such as antimalarial, antibacterial, and antifungal properties. They are an important class of heterocyclic compounds synthesized by multicomponent reactions.…”