Recent trends in layered double hydroxides based electrochemical and optical (bio)sensors for screening of emerging pharmaceutical compounds

Sohrabi, Hessamaddin; Dezhakam, Ehsan; Khataee, Alireza; Nozohouri, Ehsan; Majidi, Mir Reza; Mohseni, Nazanin; Trofimov, Evgeny; Yoon, Yong Jin

doi:10.1016/j.envres.2022.113068

Cited by 24 publications

(2 citation statements)

References 101 publications

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“…Indeed, LDHs have been used as electrode materials for at least two decades (Figure 2), as evidenced by the abundant literature described in review articles published in the last two years. LDH‐based electrodes are used to energy storage as supercapacitors [11], to electrocatalysis for oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) [12] and also in electroanalysis with the design of sensors and biosensors [3, 8, 13] for the quantification of small biomarkers [14], emerging pharmaceutical compounds [15], pesticides [16] or heavy metals [17]. Among all these sensing devices, TM‐based LDHs seem to play a key role with their own electrocatalytic properties towards some analyte molecules, such as H 2 O 2 , glucose and glyphosate.…”

Section: Introductionmentioning

confidence: 99%

Recent advances in layered double hydroxides‐based electrochemical sensors: Insight in transition metal contribution

Mousty

Farhat

2023

Electroanalysis

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Among the nanomaterials reported in the literature, layered double hydroxides (LDHs) are considered promising for the electrochemical sensor technology. Transition metal-based layered double hydroxides (TM-LDHs) show excellent electrocatalytic properties that facilitate redox reactions with analytes, e. g. H 2 O 2 , glucose or glyphosate. Elaboration of porous nano-structures with TM-LDHs nanosheets on the electrode surface allows a rapid diffusion of the analytes and a good accessibility of the TM active sites. An association of TM-LDHs with conductive materials, e. g. graphene or metal nanoparticles (M-NPs), improves the electronic conductivity in the LDH-based composites and also the electrocatalytic activity. With a selection of recent publications, the present mini-review aims to discuss about the specific electrocatalytic role played by TMs (Ni, Co, Cu, Mn and Fe) present in the LDH layers on the performance (sensitivity and detection limit) of these TM-LDHs-based sensors.

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Section: Introductionmentioning

confidence: 99%

Recent advances in layered double hydroxides‐based electrochemical sensors: Insight in transition metal contribution

Mousty

Farhat

2023

Electroanalysis

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“…15 LDHs can be obtained from both naturally occurring minerals and artificial minerals. 16 Hence, they are studied in a variety of applications such as wastewater treatment, 17 drug delivery, 18 polymer nanocomposite, 19 catalysis, 20 and energy storage. 21 There has been extensive research on transition metal-based LDHs due to their accessibility and rich resource content which also makes them an appealing alternative to noble metals.…”

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confidence: 99%

Facile Electrochemical Determination of Nilutamide with the Fabrication of Nickel-Aluminum Layered Double Hydroxide as an Efficient Electrocatalyst

Ragumoorthy,

Nataraj,

Chen

et al. 2023

J. Electrochem. Soc.

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Layered Double Hydroxides (LDHs), a class of anionic clays have garnered significant attention as a potential electrochemical active material. Due to their unique properties such as high surface area, high electrical conductivity, improved active sites, and tunable capability, they have been extensively used in the field of electrochemical sensors. On the other hand, nilutamide (NLD) is an anti-androgen drug used for the treatment of prostate cancer. However, excessive usage can lead to severe effects, thus making it essential for sensitive and selective NLD detection in the environment. Herein, we have prepared nickel aluminum (NiAl) LDH as an efficient electrode material for the electrochemical detection of nilutamide (NLD). The NiAl-LDH was obtained by a simple coprecipitation method. The physicochemical analysis was carried out using various analytical techniques including XRD, FT-IR, XPS, and Raman, which confirmed its successful formation. Further, FESEM and TEM analysis of NiAl-LDH were exhibited to prove the topological structures of the as-prepared material. The glassy carbon electrode was modified with the prepared NiAl-LDH and its electrochemical performance was studied with cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. The modified NiAl-LDH/GCE displayed excellent electrocatalytic activity towards the reduction of NLD at −0.55 V with a wide linear range of 0.029–1543.8 μM. It also exhibits a lower detection limit of 0.005 μM with a sensitivity of 15.64 μA μM−1 cm−2. Moreover, other potential interfering compounds showed no interference effect on NLD sensing. Also, the detection of NLD in spiked river water samples verified the fabricated electrode’s real-time applicability.

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Nanozyme‐Enhanced Electrochemical Biosensors: Mechanisms and Applications

Yang,

Guo,

Wang

et al. 2023

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Nanozymes, as innovative materials, have demonstrated remarkable potential in the field of electrochemical biosensors. This article provides an overview of the mechanisms and extensive practical applications of nanozymes in electrochemical biosensors. First, the definition and characteristics of nanozymes are introduced, emphasizing their significant role in constructing efficient sensors. Subsequently, several common categories of nanozyme materials are delved into, including metal‐based, carbon‐based, metal‐organic framework, and layered double hydroxide nanostructures, discussing their applications in electrochemical biosensors. Regarding their mechanisms, two key roles of nanozymes are particularly focused in electrochemical biosensors: selective enhancement and signal amplification, which crucially support the enhancement of sensor performance. In terms of practical applications, the widespread use of nanozyme‐based electrochemical biosensors are showcased in various domains. From detecting biomolecules, pollutants, nucleic acids, proteins, to cells, providing robust means for high‐sensitivity detection. Furthermore, insights into the future development of nanozyme‐based electrochemical biosensors is provided, encompassing improvements and optimizations of nanozyme materials, innovative sensor design and integration, and the expansion of application fields through interdisciplinary collaboration. In conclusion, this article systematically presents the mechanisms and applications of nanozymes in electrochemical biosensors, offering valuable references and prospects for research and development in this field.

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Recent trends in layered double hydroxides based electrochemical and optical (bio)sensors for screening of emerging pharmaceutical compounds

Cited by 24 publications

References 101 publications

Recent advances in layered double hydroxides‐based electrochemical sensors: Insight in transition metal contribution

Recent advances in layered double hydroxides‐based electrochemical sensors: Insight in transition metal contribution

Facile Electrochemical Determination of Nilutamide with the Fabrication of Nickel-Aluminum Layered Double Hydroxide as an Efficient Electrocatalyst

Nanozyme‐Enhanced Electrochemical Biosensors: Mechanisms and Applications

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