Recent surgical options for vestibular vertigo

Volkenstein, Stefan; Dazert, Stefan

doi:10.3205/cto000140

Cited by 4 publications

(2 citation statements)

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“…In the surgical treatment of Menière's disease, procedures can be divided into destructive and non-destructive therapies, due to their effect on the vestibular function [ 3 , 4 ]. One possible treatment option is the non-destructive endolymphatic sac surgery (ELS).…”

Section: Introductionmentioning

confidence: 99%

Is endolymphatic sac surgery an efficient treatment of Menière's disease patients? A systematic literature search and meta-analysis

Szott

Westhofen

Hackenberg

2022

Eur Arch Otorhinolaryngol

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Purpose The purpose of this work is to assess the treatment efficiency of endolymphatic sac surgery in patients with Menière's disease. Methods This study provides a systematic literature review and meta-analysis based on the guidelines of the Cochrane Collaboration and the Preferred Reporting Items for Systematic reviews and Meta-Analyses protocol. The main inclusion criteria of the literature review were the classification categories according to the American Academy of Otolaryngology-Head and Neck Surgery guidelines of 1985 and 1995. Results An effect of 9.25 dB postoperative weighted average hearing loss in surgically treated individuals is classified as "clinically not significant" according to American Academy of Otolaryngology-Head and Neck Surgery 85/95. In contrast, the deterioration by 26.23% in speech comprehension is considered as "clinically significant." An improvement of functional level scale assessment by two categories and vertigo control by assessment in category B can be observed. Conclusion The findings of this meta-analysis indicate that endolymphatic sac surgery may be beneficial as a treatment for Menière's disease in terms of a positive impact on functional level scale and vertigo control while yielding a negative impact on pure tone average hearing loss and on speech comprehension.

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Section: Introductionmentioning

confidence: 99%

Is endolymphatic sac surgery an efficient treatment of Menière's disease patients? A systematic literature search and meta-analysis

Szott

Westhofen

Hackenberg

2022

Eur Arch Otorhinolaryngol

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“…However, there is heated debate among ENT specialists as to whether such surgery should be performed. All the available surgical procedures and their possible indications have been summarized in ( 228 ).…”

Section: Rehabilitation and Treatment Strategies For Vestibular Disor...mentioning

confidence: 99%

Vestibular Deficits in Deafness: Clinical Presentation, Animal Modeling, and Treatment Solutions

2022

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The inner ear is responsible for both hearing and balance. These functions are dependent on the correct functioning of mechanosensitive hair cells, which convert sound- and motion-induced stimuli into electrical signals conveyed to the brain. During evolution of the inner ear, the major changes occurred in the hearing organ, whereas the structure of the vestibular organs remained constant in all vertebrates over the same period. Vestibular deficits are highly prevalent in humans, due to multiple intersecting causes: genetics, environmental factors, ototoxic drugs, infections and aging. Studies of deafness genes associated with balance deficits and their corresponding animal models have shed light on the development and function of these two sensory systems. Bilateral vestibular deficits often impair individual postural control, gaze stabilization, locomotion and spatial orientation. The resulting dizziness, vertigo, and/or falls (frequent in elderly populations) greatly affect patient quality of life. In the absence of treatment, prosthetic devices, such as vestibular implants, providing information about the direction, amplitude and velocity of body movements, are being developed and have given promising results in animal models and humans. Novel methods and techniques have led to major progress in gene therapies targeting the inner ear (gene supplementation and gene editing), 3D inner ear organoids and reprograming protocols for generating hair cell-like cells. These rapid advances in multiscale approaches covering basic research, clinical diagnostics and therapies are fostering interdisciplinary research to develop personalized treatments for vestibular disorders.

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New marsupialization technique in endolymphatic sac surgery

Daneshi

Hosseinzadeh

Mohebbi

et al. 2020

Laryngoscope Investig Oto

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ObjectivesThe aim of the present study was to describe and evaluate the results of a new technique in endolymphatic sac decompression surgery.MethodsForty‐three patients with intractable unilateral Meniere's disease were selected. Endolymphatic sac was identified after simple mastoidectomy, and its lateral layer was incised, using a sickle knife. Outer layer of the sac was turned around and placed under the anterior bony border.ResultsMean duration of the follow‐up was 24 months. Mean tinnitus handicap index, pure tone average (PTA) on thresholds at 500, 1000, 2000, and 4000 Hz, mean speech reception threshold, mean speech discrimination score, hearing stage, and mean vertigo score before and after surgery were evaluated.ConclusionThe new marsupialization technique with anterior bony border is a safe and effective way to improve tinnitus, vertigo, and ear fullness among these patients. According to PTA and hearing stage, this surgery can control progressive hearing loss.Level of Evidence3

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Recent surgical options for vestibular vertigo

Cited by 4 publications

References 290 publications

Is endolymphatic sac surgery an efficient treatment of Menière's disease patients? A systematic literature search and meta-analysis

Is endolymphatic sac surgery an efficient treatment of Menière's disease patients? A systematic literature search and meta-analysis

Vestibular Deficits in Deafness: Clinical Presentation, Animal Modeling, and Treatment Solutions

New marsupialization technique in endolymphatic sac surgery

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