Abstract:Neurodegeneration include disease of the central nervous system (CNS) such as Parkinson’s disease (PD). The sign of this disease include destruction of dopaminergic neuronal cells. Main causes of this disease are unknown, but several studies reported polygenic causes. These include free radicals, malfunction of mitochondria, protein oxidation and DNA denaturation. Several reports implicated the involvement of oxygen species and stresses cause by over accumulation of reactive oxygen species in the contribution … Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.