Recent Progress on Gold-Nanocluster-Based Fluorescent Probe for Environmental Analysis and Biological Sensing

Liu, Mingxian; Tang, Fenglin; Yang, Zhengli; Xu, Jing; Yang, Xiupei

doi:10.1155/2019/1095148

Cited by 24 publications

(16 citation statements)

References 94 publications

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“…While, nanoparticles to clusters methods are etching surface atoms of gold nanoparticles by appropriate ligand, or solvents [ 31 ]. AuNCs are characterized by photoluminescence [ 32 ]and high catalytic properties [ 33 ]; on the other end, AuNCs do not present the surface plasmon resonance properties characteristic of the AuNPs and AuNRs [ 9 ]. Zhang et al discussed synthesis methods [ 28 ] and biomedical and biosensing applications of Au nanoclusters in a recent review [ 34 ].…”

Section: Nanomaterialsmentioning

confidence: 99%

Nanomaterial application in bio/sensors for the detection of infectious diseases

Sheikhzadeh

Beni

Zourob

2021

Talanta

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Infectious diseases are a potential risk for public health and the global economy. Fast and accurate detection of the pathogens that cause these infections is important to avoid the transmission of the diseases. Conventional methods for the detection of these microorganisms are time-consuming, costly, and not applicable for on-site monitoring. Biosensors can provide a fast, reliable, and point of care diagnostic. Nanomaterials, due to their outstanding electrical, chemical, and optical features, have become key players in the area of biosensors. This review will cover different nanomaterials that employed in electrochemical, optical, and instrumental biosensors for infectious disease diagnosis and how these contributed to enhancing the sensitivity and rapidity of the various sensing platforms. Examples of nanomaterial synthesis methods as well as a comprehensive description of their properties are explained. Moreover, when available, comparative data, in the presence and absence of the nanomaterials, have been reported to further highlight how the usage of nanomaterials enhances the performances of the sensor.

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Section: Nanomaterialsmentioning

confidence: 99%

Nanomaterial application in bio/sensors for the detection of infectious diseases

Sheikhzadeh

Beni

Zourob

2021

Talanta

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“…As a kind of promising nanomaterials, metal nanoclusters (NCs) have sparked wide-spread attention. In recent years, gold nanoparticles (AuNPs) have been applied to biomedicine and biological sensing [1][2][3][4][5] due to their biocompatibility and unique physical properties. AuNPs are one of the most promising catalysts, in spite of bulk Au as an inactive material [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Spin-Orbit Coupling Effect on the Electrophilicity Index, Chemical Potential, Hardness and Softness of Neutral Gold Clusters: A Relativistic Ab-initio Study

Sani

2021

HighTech. Innov. J.

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Electrophilicity index (𝜔) is related to the energy lowering associated with a maximum amount of electron flow between a donor and an acceptor and possesses adequate information regarding structure, stability, reactivity and interactions. Chemical potential (μ) measures charge transfer from a system to another having a lower value of μ, while chemical hardness (η) is a measure of characterizing relative stability of clusters. The main purpose of the present research work is to examine the Spin-Orbit Coupling (SOC) effect on the behavior of the electrophilicity index, chemical potential, hardness and softness of neutral gold clusters Aun (n=2-6). Using the second-order Douglas-Kroll-Hess Hamiltonian, geometries are optimized at the DKH2-B3P86/DZP-DKH level of theory. Spin-orbit coupling energies are computed using the fourth-order Douglas-Kroll-Hess Hamiltonian, generalized Hartree-Fock method and all-electron relativistic double-ζ level basis set. Then, spin-orbit coupling (SOC) corrections to the electrophilicity index, chemical potential, hardness and softness are calculated. It is revealed that spin-orbit correction to the vertical chemical hardness has important effect on Au3 and Au6, i.e. SOC decreases (increases) the hardness of gold trimer (hexamer). Due to the relationship between hardness and softness, σ = , inclusion of spin-orbit coupling increases (decreases) the softness of Au3 (Au6) and thus destabilizes (stabilizes) it. Spin-orbit coupling (SOC) also has more important effect on the chemical potential of Au3 by decreasing its value. It is found that spin-orbit coupling has considerable effect on the electrophilicity index of gold trimer and greatly increases its value. Furthermore, SOC increases the maximal charge acceptance of Au3 more and thus destabilizes it more. As a result, spin-orbit coupling effect appears to be important in calculating the electrophilicity index of the gold trimer. Doi: 10.28991/HIJ-2021-02-01-05 Full Text: PDF

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“…Recently, alloy, core-shell nanoparticles and biametallic nanostrucrued material played important role for design of electrochemical biosensor because of their excellent optical, magnetic, and catalytic properties. They offer better sensing properties as compare to single nanometallic material [7][8][9].The conjugation of metal particles Pb 2+ with bioreceptors, for example, proteins, antibodies, or nucleic acids, can increase the selectivity and lower the limit of detection (LOD) of nanobiosensors [10,11].…”

Section: Introductionmentioning

confidence: 99%

Rapid and selective electrochemical detection of pb2+ ions using aptamer-conjugated alloy nanoparticles

et al. 2020

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Heavy metals are an important class of technogenic toxicants that pollute rivers and underground water. Here we proposed the use of electrochemical methods using silver (Ag)-gold (Au) alloy nanoparticle (NP)-aptamer-modified glassy carbon electrode (GCE) for the detection of lead ions (Pb 2+). Alloy Ag-Au NPs were electrodeposited on the electrode using the potentiostatic double-pulse method. The NPs were characterized by high-resolution transmission electron microscopy, which revealed that the average NP size was 44 nm. The binding of Pb 2+ induced conformational changes of the aptamer and corresponding modulation of electrochemical signals. As a result, we were able to detect Pb 2+ with a straight slope of 0.01-10 µg/L with limits of detection (LOD) of 0.03 × 10 −2 μg/L for CV, DPV and 0.04 × 10-2 μg/L for EIS. The minimum detectable Pb 2+ concentration was calculated to be 0.8 μM.

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Recent Progress on Gold-Nanocluster-Based Fluorescent Probe for Environmental Analysis and Biological Sensing

Cited by 24 publications

References 94 publications

Nanomaterial application in bio/sensors for the detection of infectious diseases

Nanomaterial application in bio/sensors for the detection of infectious diseases

Spin-Orbit Coupling Effect on the Electrophilicity Index, Chemical Potential, Hardness and Softness of Neutral Gold Clusters: A Relativistic Ab-initio Study

Rapid and selective electrochemical detection of pb2+ ions using aptamer-conjugated alloy nanoparticles

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