Recent Progress in the Synthetic Assembly of 2-Cyclopentenones

Abstract

An overview of the most important synthetic strategies currently available for the preparation of cyclopent-2-enones is presented and illustrated with recent applications.

Hypervalent Iodine Mediated Sulfonamide Synthesis

“…1 [8] Prepared according to the general procedure. [31] All the geometry optimizations were carried out at the M06 level of theory with the LANL2DZ basis set (Los Alamos National Laboratory 2 double ). Purification by thin layer chromatography using ethyl acetate/hexane (1:2) gave the title product as a black solid in 54 % yield.…”

The chemistry of the carbon-transition metal double and triple bond: Annual survey covering the year 2014

“…Specific compounds or compound classes represented include: (1) tetrahydropyrans [53]; (2) cyclopentenones [54]; (3) 3,4,5-trisubstituted isoxazolines [55]; (4) carbocyclic nucleosides [56]; (5) lycopodium alkaloids [57,58]; (6) cyclic hydrazines and azo compounds [59]; (7) tropone and tropolone natural products [60]; (8) seven-membered ring natural products [61]; [62]; (9) tetrahydroisoquinoline-3-carboxylic acid derivatives [63]; (10) chalcones and their heterocyclic derivatives [64]; (11) marine-derived cyclic ethers [65]; (12) pericosine and related marinederived carbasugar natural products [66]; (13) carbohydrate derived macrocyclic compounds [67]; (14) neurotrophic natural products [68]; (15) isodon diterpenes [69]; (16) non-isoprenoid polyene natural products [70]; (17) heterophosphacyclanes [71]; (18) chlorosulfolipids [72]; (19) seven-membered ring sulfur heterocycles; (20) organic cage compounds [73]; (21) presilphiperfolanols [74]; (22) pleuromutilin [75]; (23) hyperforin [76]; (24)…”

Tetrasubstituted cyclopentenone‐based fluorescent chemosensors for the selective detection of Fe3+ and Cu2+ ions

“…In the present study we synthesized 4‐hydroxy cyclopentenone‐based chemosensors 3 and 5 by base catalyzed condensation of 1,5‐diphenyl‐pentane‐1,3,5‐trione 1 with 1,2‐diphenylethane‐1,2‐dione and 2,2′‐thenil . Even though this chemistry including synthesis, spectral, chemical and biological properties of cyclopentenones have been previously well explored, to the best of our knowledge there have been no reports regarding the metal‐sensing application of cyclopentenones. Details regarding the capability of cyclopentenones 3 and 5 to act as fluorescent turn‐off and turn‐on chemosensors, respectively, to selectively detect Fe 3+ and Cu 2+ are the subject matter of this paper.…”