Recent Progress in Metal-Organic Framework Based Fluorescent Sensors for Hazardous Materials Detection

Abstract

Population growth and industrial development have exacerbated environmental pollution of both land and aquatic environments with toxic and harmful materials. Luminescence-based chemical sensors crafted for specific hazardous substances operate on host-guest interactions, leading to the detection of target molecules down to the nanomolar range. Particularly, the luminescence-based sensors constructed on the basis of metal-organic frameworks (MOFs) are of increasing interest, as they can not only compensate for the shortcomings of traditional detection techniques, but also can provide more sensitive detection for analytes. Recent years have seen MOFs-based fluorescent sensors show outstanding advantages in the field of hazardous substance identification and detection. Here, we critically discuss the application of MOFs for the detection of a broad scope of hazardous substances, including hazardous gases, heavy metal ions, radioactive ions, antibiotics, pesticides, nitro-explosives, and some harmful solvents as well as luminous and sensing mechanisms of MOF-based fluorescent sensors. The outlook and several crucial issues of this area are also discussed, with the expectation that it may help arouse widespread attention on exploring fluorescent MOFs (LMOFs) in potential sensing applications.

Application of MOF-based nanotherapeutics in light-mediated cancer diagnosis and therapy

“…Luminescent characteristics together with size/shape selective properties of NMOFs facilitated the diagnosis of various diseases [35][36][37]. MOFs-based nanotherapeutics can be enriched at the tumor site for passive targeting through the high permeability and retention effects of solid tumors, or actively targeted through binding to tumor-specific receptors, thereby increasing the effective enrichment of imaging agents at the tumor site and enhancing the imaging effect [38].…”

Highlighting Recent Crystalline Engineering Aspects of Luminescent Coordination Polymers Based on F-Elements and Ditopic Aliphatic Ligands

“…sensing, gas storage, and drug delivery were thoroughly investigated, becoming mature areas [8][9][10][11][12][13][14][15][16][17][18][19][20][21].…”

“…These materials have been extensivelt studied in recent decades due to their multifunctional properties, which are intimately related to their structural features [5][6][7]. Properties such as luminescence, catalysis, sensing, gas storage, and drug delivery were thoroughly investigated, becoming mature areas [8][9][10][11][12][13][14][15][16][17][18][19][20][21].…”

In Search of Preferential Macrocyclic Hosts for Sulfur Mustard Sensing and Recognition: A Computational Investigation through the New Composite Method r2SCAN-3c of the Key Factors Influencing the Host-Guest Interactions

“…Some decontamination processes have been developed to eliminate the SM such as chemical degradation by hydrolysis or oxidation [ 7 , 8 ]. An alternative strategy, based on the complexation of harmful substances [ 9 , 10 , 11 , 12 ] by macrocyclic systems offers new perspectives to address the issue of capturing and storing hazardous substances. Supramolecular chemistry is mainly concerned with the study of the host-guest complexes in which two or more neutral or charged molecules bind to each other via non-covalent interactions [ 13 , 14 , 15 ]; these interactions are the main driving forces of the complexation process, which leads to the modification of the physicochemical properties of host-guest complexes [ 16 , 17 , 18 , 19 , 20 ].…”