Recent progress in metabolic reprogramming in gestational diabetes mellitus: a review
Ya-ping Xie,
Shu Lin,
Bao-yuan Xie
et al.
Abstract:Gestational diabetes mellitus is a prevalent metabolic disease that can impact the normal course of pregnancy and delivery, leading to adverse outcomes for both mother and child. Its pathogenesis is complex and involves various factors, such as insulin resistance and β-cell dysfunction. Metabolic reprogramming, which involves mitochondrial oxidative phosphorylation and glycolysis, is crucial for maintaining human metabolic balance and is involved in the pathogenesis and progression of gestational diabetes mell… Show more
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