Recent Progress in Mass Spectrometry-Based Metabolomics in Major Depressive Disorder Research
Mingxia Liu,
Wen Ma,
Yi He
et al.
Abstract:Major depressive disorder (MDD) is a serious mental illness with a heavy social burden, but its underlying molecular mechanisms remain unclear. Mass spectrometry (MS)-based metabolomics is providing new insights into the heterogeneous pathophysiology, diagnosis, treatment, and prognosis of MDD by revealing multi-parametric biomarker signatures at the metabolite level. In this comprehensive review, recent developments of MS-based metabolomics in MDD research are summarized from the perspective of analytical pla… Show more
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