In this paper, the almost periodic solutions for discontinuous impulsive gene regulatory networks (GRNs) are investigated. Firstly, the concept of almost periodicity is introduced for the impulsive model under consideration. Secondly, sufficient conditions are presented for the existence, uniqueness, and global exponential stability of almost periodic solutions. To this end, an estimate of the Cauchy matrix of the model of GRNs is established. Finally, the obtained results as well as the control power of the impulses are demonstrated via examples. This research contributes to the development of the qualitative theory of impulsive GRNs in almost periodic environment.