Recent Progress in Biomedical Sensors Based on Conducting Polymer Hydrogels

Abstract

Biosensors are increasingly taking a more active role in health science. The current needs for the constant monitoring of biomedical signals, as well as the growing spending on public health, make it necessary to search for materials with a combination of properties such as biocompatibility, electroactivity, resorption, and high selectivity to certain bioanalytes. Conducting polymer hydrogels seem to be a very promising materials, since they present many of the necessary properties to be used as biosensors. Furthermore, their properties can be shaped and enhanced by designing conductive polymer hydrogel-based composites with more specific functionalities depending on the end application. This work will review the recent state of the art of different biological hydrogels for biosensor applications, discuss the properties of the different components alone and in combination, and reveal their high potential as candidate materials in the fabrication of all-organic diagnostic, wearable, and implantable sensor devices.

Degradable Polymeric Bio(nano)materials and Their Biomedical Applications: A Comprehensive Overview and Recent Updates

“…They can be used for analysis of clinical samples or for ex vivo and in vivo monitoring of different physiological changes within the human body. Chitosan-based films have been applied to the cholesterol biosensor to improve its sensitivity [ 434 , 435 , 436 , 437 , 438 ].…”

The latest research progress of conductive hydrogels in the field of electrophysiological signal acquisition

“…56 The conductivity enhancement of conducting polymers is mainly due to the fact that doping stabilizes the conjugation of the polymer double bonds, and the π-electrons of the double bonds of the conducting polymer structure are displaced and move along the polymer chain, thus generating an electric current. 57 By combining a conductive polymer and a hydrogel network, the pure conductive polymer hydrogels prepared have high electrical conductivity, but their mechanical properties are to be improved to meet the application requirements, so there is still a great challenge to be overcome for balancing the electrical conductivity and the mechanical properties of conductive polymer hydrogels. 58…”

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