“…[20] Because of the important features of the motif described above, and as a continuation of our work directed towards the preparation of valuable enantioenriched building blocks, [21][22][23][24] we report herein the synthesis of novel families of enantioenriched cis-monofluorinated carbocyclic alcohols and trans-difluorinated indans, 1,2,3,4-tetrahydronaphthalenes, N-Boc tetrahydroquinolines and chromans 8, by deoxofluorination of the corresponding cis-fluoro alcohols 7 (Scheme 1). The enantiomerically enriched 2-fluoro inden-1-ol (7, X = CH 2 , n = 0) and 2-fluoro 1,2,3,4-tetrahydronaphthalen-1-ol (7, X = CH 2 , n = 1) derivatives would result from transition metal-catalyzed asymmetric transfer hydrogenation/dynamic kinetic resolution (ATH/DKR) [25][26][27][28][29][30][31][32] of 2-fluoro-2,3-dihydro-1H-inden-1-ones and 2- www.eurjoc.org fluoro-3,4-dihydronaphthalen-1(2H)-ones 6 whereas we previously achieved the preparation of enantioenriched fluoro chromanols (7, X = O) [33] and N-Boc fluoro hydroxy dihydroquinolines (7, X = NBoc) [34] derivatives.…”