Recent Point of Care (PoC) Electrochemical Testing Trends of New Diagnostics Platforms for Vitamin D

Abstract

Recent advancements in electrochemical sensors for the detection of vitamins, particularly vitamin D, have drawn a lot of attention due to their outstanding advantages of simplicity and high sensitivity. For the purpose of detecting vitamin D in this circumstance, recent research has focused on developing electrochemical sensors. Although there is always space for improvement, electrochemical sensors for vitamin D detection and its transformation into point‐of‐care devices have made great strides lately. For example, the development of innovative electrode materials that can increase sensitivity and selectivity continues to garner a lot of interest. New suggestions on adsorptive detections using vitamin D carriers like nanoclays or hydroxyapatite‐clay composites are being developed. These biosensors hold huge potential for the detection of cheap, disposable, and biodegradable solutions. Also, the biosensor could monitor the depletion of vitamin levels, providing a real‐time platform for the Internet of Medical Things, fifth‐generation wireless communications, and smartphone‐based electrochemical sensors. Currently, electrochemical sensors based on smartphones have been proposed to detect using various biomarkers for monitoring several changes in glucose, etc. We believe smartphone‐based electrochemical sensors and adsorptive sensing platforms provides a novel way toward point‐of‐care tests for identifying especially vitamin D deficiency and real‐time monitoring

P-EcStat: A Versatile Design of Photoelectrochemical and Electrochemical Sensing System with Smartphone Interface via Bluetooth Low Energy

“…In addition, the same electrical form of the stimulated signal and the collected signal of the EC sensors leads to easy miniaturization of the measurement systems, making them flexible and reducing the cost. Due to their flexibility, reliability, fast response, and cost-effectiveness, EC sensors are ideal for pointof-care (POC) applications such as the ubiquitous glucose meter [37][38][39][40]. In addition, electrochemical sensors have also been widely used in industrial and civil environments to detect toxic gases [41].…”