Recent methodological advances towards single-cell proteomics
Sooyeon KIM,
Latiefa KAMARULZAMAN,
Yuichi TANIGUCHI
Abstract:Studying the central dogma at the single-cell level has gained increasing attention to reveal hidden cell lineages and functions that cannot be studied using traditional bulk analyses. Nonetheless, most single-cell studies exploiting genomic and transcriptomic levels fail to address information on proteins that are central to many important biological processes. Single-cell proteomics enables understanding of the functional status of individual cells and is particularly crucial when the specimen is composed of… Show more
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