Recent developments towards portable point-of-care diagnostic devices for pathogen detection

Roy, Sharmili; Arshad, Fareeha; Eissa, Shimaa; Safavieh, Mohammadali; Al-Attas, Sanaa Ghazi; Ahmed, Minhaz Uddin; Zourob, Mohammed

doi:10.1039/d1sd00017a

Cited by 36 publications

(25 citation statements)

References 224 publications

(297 reference statements)

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“…A microfluidics-based on-chip artificial pore has been reported to sense the bacterial pathogens [ 124 ]. The on-site detection of pathogens using POC devices mostly comprise lateral flow tests and lateral flow assays [ 125 , 126 ]. Further, the integration of sensing modalities with smartphones has been easily implemented in pathogen detection [ 127 , 128 ].…”

Section: Emerging Pathogen-detection Techniquesmentioning

confidence: 99%

Current Scenario of Pathogen Detection Techniques in Agro-Food Sector

Nehra

Kumar

et al. 2022

Biosensors

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Over the past-decade, agricultural products (such as vegetables and fruits) have been reported as the major vehicles for foodborne diseases, which are limiting food resources. The spread of infectious diseases due to foodborne pathogens poses a global threat to human health and the economy. The accurate and timely detection of infectious disease and of causative pathogens is crucial in the prevention and treatment of disease. Negligence in the detection of pathogenic substances can be catastrophic and lead to a pandemic. Despite the revolution in health diagnostics, much attention has been paid to the agro-food sector regarding the detection of food contaminants (such as pathogens). The conventional analytical techniques for pathogen detection are reliable and still in operation. However, laborious procedures and time-consuming detection via these approaches emphasize the need for simple, easy-to-use, and affordable detection techniques. The rapid detection of pathogens from food is essential to avoid the morbidity and mortality originating from the suboptimal nature of empiric pathogen treatment. This review critically discusses both the conventional and emerging bio-molecular approaches for pathogen detection in agro-food.

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Section: Emerging Pathogen-detection Techniquesmentioning

confidence: 99%

Current Scenario of Pathogen Detection Techniques in Agro-Food Sector

Nehra

Kumar

et al. 2022

Biosensors

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“…The previous decade has seen the development of impressive biosensors that allow for sensitive and selective detection of multiple biomarkers without extensive prerequisites. 9–15…”

Section: Introductionmentioning

confidence: 99%

“…The previous decade has seen the development of impressive biosensors that allow for sensitive and selective detection of multiple biomarkers without extensive prerequisites. [9][10][11][12][13][14][15] Conventional diagnostic techniques like immunoassays, agglutination, polymerase chain reaction (PCR), pathogen culturing among others, involve expensive and complex equipment, as well as require trained professionals to handle the system. 16 In addition, they are costly to prepare, operate, and maintain; therefore, they are not user-friendly and not easily accessible to those in under-developed areas.…”

Section: Introductionmentioning

confidence: 99%

Nanozyme-based sensors for detection of food biomarkers: a review

et al. 2022

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“…In several studies, 2D material-based biosensors have been utilized to detect different metabolic imperfections and environmental risk factors, including pathogens and toxins. 22,32 With these considerations in mind, nZrO 2 -RGO nanocomposite seems to be a highly efficient immobilization matrix for the development of a nanobiosensing platform in which both components synergistically compensate for each other's shortcomings.…”

Section: Introductionmentioning

confidence: 99%