Recent Developments in Ion Mobility Spectrometry

Borsdorf, Helko; Mayer, Thomas; Zarejousheghani, Mashaalah; Eiceman, Gary A.

doi:10.1080/05704928.2011.582658

Cited by 160 publications

(112 citation statements)

References 333 publications

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“…The processes taking place in the ionization chamber of the IMS-device depend on many factors [1][2][3]. However, we know that many explosives, e.g.…”

Section: Introductionmentioning

confidence: 99%

Ion Mobility Spectrometer for Rapid Simultaneous Detection of Positive and Negative Ions

Vasilyev

Першенков

Belyakov

et al. 2016

3rd International Conference on Nanotechnologies and Biomedical Engineering

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Abstract-Ion Mobility Spectrometry (IMS) is a common technology used for rapid detection of trace amounts of explosives (mostly forming negative ions) and drugs (forming positive ions). Emergency chemically hazardous substances widely used in modern industry. Some emergency chemically hazardous substances form positive ions, others form negative ions. Therefore, for the detection of different substances in real time is required to apply the structure of two IMS-detectors. The article describes a device for the simultaneous detection of ions of both polarities with the ionization source based on a pulsed corona discharge. Authors investigated the advantages and disadvantages of such construction compared to unipolar cell in terms of sensitivity. Experimental results have demonstrated.

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“…The processes taking place in the ionization chamber of the IMS-device depend on many factors [1][2][3]. However, we know that many explosives, e.g.…”

Section: Introductionmentioning

confidence: 99%

Ion Mobility Spectrometer for Rapid Simultaneous Detection of Positive and Negative Ions

Vasilyev

Першенков

Belyakov

et al. 2016

3rd International Conference on Nanotechnologies and Biomedical Engineering

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“…In more modern applications, even the study of protein-protein and non-covalent proteinligand complexes is possible (Ruotolo et al 2008, Politis et al 2010. Particularly as portable analyzers, ion mobility spectro meters exist in numbers and locations at present unparalleled by any other comparably sophisticated chemical analyzer (Borsdorf et al 2011 ).…”

Section: Introductionmentioning

confidence: 99%

Pulsed electron beams in ion mobility spectrometry

Baether¹,

Zimmermann²,

Gunzer³

2012

Reviews in Analytical Chemistry

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Abstract:Ion mobility spectrometry is a well-known technique used to analyze trace gases in ambient air. Typically, it works by employing a radioactive source to provide electrons with high energy to ionize the analytes in a series of chemical reactions. During the past ten years non-radioactive sources have been one of the subjects of interest in ion mobility spectrometry, initially in order to replace radioactive sources as a result of general security and regulatory concerns. Among these non-radioactive sources especially pulsed sources have recently been shown to additionally improve the analytic information provided by ion mobility spectrometers. In this review we will describe the progress regarding the application of pulsed non-radioactive electron sources in ion mobility spectrometry and show the recent analytical advances that have been achieved by using pulsed electron beams.

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“…The IMS is operated in either a positive mode, where only the positively charged ions are accelerated through the drift tube towards the detector, or in a negative mode, where only the negatively charged ions are detected. 2 Due to the charge transfer reaction between sample molecules and RIP molecules and the general conservation of charges, it is in principle possible to form a relation between the ratio of signal intensities (RIP and analyte) and analyte concentration. Examples are the detection of TNT, 3 acetone, 4 and ethanol, 5 but also more complex substances such as morphine and noscapine.…”

Section: Introductionmentioning

confidence: 99%

Quantitative information in decay curves obtained with a pulsed ion mobility spectrometer

Baether

Zimmermann

Gunzer

2012

Analyst

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Ion mobility spectrometry (IMS) is well known for its very high sensitivity, and thus IMS spectra are commonly used in the identification of trace gases. Extracting quantitative information from IMS spectra is, in contrast, difficult, especially regarding the reproducibility due to the nature of the processes involved in the measurement of the spectra. Here we present data extracted from signal decay curves obtained with a pulsed IMS, which can support the determination of substance concentrations in the lower ppb range with good stability.

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Recent Developments in Ion Mobility Spectrometry

Cited by 160 publications

References 333 publications

Ion Mobility Spectrometer for Rapid Simultaneous Detection of Positive and Negative Ions

Ion Mobility Spectrometer for Rapid Simultaneous Detection of Positive and Negative Ions

Pulsed electron beams in ion mobility spectrometry

Quantitative information in decay curves obtained with a pulsed ion mobility spectrometer

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