Recent Developments in Folate Nutrition

Naderi, Nassim; House, James D.

doi:10.1016/bs.afnr.2017.12.006

Cited by 96 publications

(78 citation statements)

References 73 publications

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“…The B vitamins (thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), vitamin B6, folate (B9), and vitamin B12) are water-soluble, and they are essential for many body functions, including catabolic metabolism and anabolic metabolism. Importantly, the active forms of thiamine, riboflavin, and niacin are essential co-enzymes playing a role in mitochondrial aerobic respiration and cellular energy production, and therefore deficiency of any one B vitamin could dysregulate the aforementioned processes [ 16 , 17 , 18 , 19 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

Dietary Micronutrient and Mineral Intake in the Mediterranean Healthy Eating, Ageing, and Lifestyle (MEAL) Study

et al. 2018

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Background: Dietary vitamins and minerals are essential compounds for the proper functioning of metabolic enzymes, regulation of gene transcription, and powering the body’s defense against oxidative stress. The aim of the present study was to investigate micronutrient consumption separately by age and sex, major dietary sources, and percentage of individuals meeting the recommended requirements according to Italian (Livelli di Assunzione di Riferimento di Nutrienti (LARN)) and European (European Food Safety Agency (EFSA)) agencies. Methods: Data were obtained from the Mediterranean Healthy Eating, Ageing, and Lifestyle (MEAL) study, which included a sample of 1838 individuals randomly collected in the city of Catania, southern Italy. A validated food frequency questionnaire was used to collect information on diet. Results: Intake of vitamin A, vitamin C, and vitamin B group (except vitamin B9) was in line with other reports and was adequate according to the guidelines, while the percentage of individuals meeting the guidelines for vitamin D, vitamin E, and vitamin B9 was about 3%, 10%, and 40%, respectively. Among minerals, intake of iron, magnesium, and selenium was adequate for most of the sample, while the percentage of individuals meeting the recommendations for calcium, sodium, and potassium intake was about 20%, 8%, and 35%, respectively. Conclusions: An important percentage of the population would benefit from campaigns raising awareness of micronutrient deficiency or excessive consumption potentially affecting their health.

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Section: Introductionmentioning

confidence: 99%

Dietary Micronutrient and Mineral Intake in the Mediterranean Healthy Eating, Ageing, and Lifestyle (MEAL) Study

et al. 2018

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“…Vitamins B 2 and B 7 have important functions with regards to cellular processes (Powers, 2003;Heidker et al, 2016). Vitamin B 9 is an essential vitamin necessary for human health and development (Ebara, 2017;Naderi and House, 2018). Vitamin K 2 has positive effects on preventing osteoporosis and cardiovascular disease, as well as aiding in blood coagulation (Mahdinia et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Microbiome and Functional Analysis of a Traditional Food Process: Isolation of a Novel Species (Vibrio hibernica) With Industrial Potential

2020

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“…For example, folates can mask the B12 deficiency favoring the progression of neurological damage [16]. The combination of these two vitamins could have a synergic effect in improving homocysteine metabolism hence the sperm quality.…”

Section: Discussionmentioning

confidence: 99%

Food Supplements in the Treatment of Male Infertility: A Critical Review on Their Formulations and Use

Garolla¹,

Petre²,

Francini-Pesenti³

et al. 2020

Preprint

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Background: Dietary supplements (DS) represent a possible approach to improve sperm parameters and male fertility. A wide range of DS containing different nutrients is now available. Although many authors demonstrated benefits from some nutrients in male infertility, their real effectiveness is still under debate. The aim of this study was to critically review the composition of DS using the Italian market as sample. Materials & Methods: Active ingredients and their minimal effective daily dose (mFED) were identified through literature search. Thereafter, we created a formula to classify the expected efficacy of each DS. Considering active ingredients, their concentration and the recommended daily dose, DS were scored into three classes of expected efficacy: higher, lower and none. Results: Twenty-one DS were identified. Most of them had a large number of ingredients, frequently at doses below mFED or with unproven efficacy. Zinc was the most common ingredient of DS (70% of products), followed by selenium, arginine, coenzyme Q and folic acid. By applying our scoring system, 9.5% of DS fell in higher class, 71.4% in lower class and 19.1% in the class with no expected efficacy. Conclusions: DS marketed in Italy for male infertility frequently include effective ingredients but also a large number of substances at insufficient dose or with no proven efficacy. Manufacturers and physicians should better consider the scientific evidence on effective ingredients and their doses before formulating and prescribing these products.

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Recent Developments in Folate Nutrition

Cited by 96 publications

References 73 publications

Dietary Micronutrient and Mineral Intake in the Mediterranean Healthy Eating, Ageing, and Lifestyle (MEAL) Study

Dietary Micronutrient and Mineral Intake in the Mediterranean Healthy Eating, Ageing, and Lifestyle (MEAL) Study

Microbiome and Functional Analysis of a Traditional Food Process: Isolation of a Novel Species (Vibrio hibernica) With Industrial Potential

Food Supplements in the Treatment of Male Infertility: A Critical Review on Their Formulations and Use

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