Recent Developments in Antibody-Based Assays for the Detection of Bacterial Toxins

Zhu, Kui; Dietrich, Richard; Didier, Andrea; Doyscher, Dominik; Märtlbauer, Erwin

doi:10.3390/toxins6041325

Cited by 50 publications

(39 citation statements)

References 131 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Nanotechnology has prospective purposes in all foodstuffs traits including processing, covering and monitoring. As results, thousands of goods 53 could be emerges based on nanotechnology in the imminent decades (Zhu 2014).…”

Section: Fig 1-application Matrix Of Nanotechnology In Food Science mentioning

confidence: 99%

“…Comparable to other prevailing technology fields, foodstuff nanotechnology has conceivable for both value and maltreatment. We must well recognize the capable and capabilities of advanced food nanotechnology before it arrives, and work to prepare for changes it will be bring (Zhu 2014).…”

Section: Fig 1-application Matrix Of Nanotechnology In Food Science mentioning

confidence: 99%

“…Besides, the successful in foodstuff nanotechnology also plays as contributor to drive the world's economic growth. Thus, the objective of this report is to present a clear picture on the usages of nanotechnology in foodstuff area emphasizing on wrapping and security applications together with the field of antibiotics (Zhu 2014).…”

Section: Fig 1-application Matrix Of Nanotechnology In Food Science mentioning

confidence: 99%

See 2 more Smart Citations

Nano-biotechnology breakthrough and food-packing industry- A Review

Helmy

2016

MBJ

View full text Add to dashboard Cite

Nanobiotechnology has been renowned as extremely essential scientific and industrialized advancements that have the actual ability to renovate virtually each feature of lifetimes and economy. Chemical and physical methods for the synthesis of nanoparticles are the common approaches, but their use is limited because they are costly and harmful to the environment. In this method, the biological systems such as bacteria, fungi, plants were used to transform the organic metal into metal nanoparticles via the reactive capacity of proteins and metabolites present in these organisms. The biogenic synthesis using biological routes especially fungal pathways is, therefore, the best choice. The use of fungi in the green synthesis of metal nanoparticles has been reported in several promising studies, since fungi contain enzymes and proteins as reducing agents and can be invariably used for the synthesis of metal nanoparticles from their salts. Generally, microbial nanobiotechnology can adapt of packaging stuff, rising barrier characteristics, refining mechanical and heat-resistance, evolving functioning antimicrobial exteriors, and generates nano-biodegradable packaging stuffs. Improving intelligent packaging to elevate the nutritional goods validity timing via nanobiotechnology became the ambition of many corporations. This review will focus on tremendous benefits of nanobiotechnology in nutrition trade concerning Foodstuff Wrapping systems and materials. Such packaging (wrapping) structures would be able to fix minor holes/tears, react to ecological conditions as temperature and/or moisture changes and attentive the client if the food is spoiled. Nanobiotechnology has utilized in inventive improvement of biosensors for recognition of pathogens and chemical pollutants. Elaboration of food analytical approaches for the uncovering of tiny aggregates of a chemical and/or any microbial pollutant during food processing is an extra prospective practice of nanobiotechnology. This will leads to further safety for the food handling approaches.Key words -Biosynthesis -microbial nanobiotechnology -nanoparticles'fungal biosynthesis. IntroductionThe global economy in the 21 th century stems the awareness and thoughts rather than the production and trade applications of physical commodities. Thus, nanotechnology developed in the beginning of this novel era. Nanotechnology, the innovative science arises, has a powerful impression on the world's population than any other previous cognizance and techniques. This is owing to the nanotechnology not only will occupy a major portion of our economy, but also, will form the foundation for revolutionary discoveries and advancements in decades to be coming. Besides, the production of nanotechnology can greatly create wealth; improve health, and almost

show abstract

Section: Fig 1-application Matrix Of Nanotechnology In Food Science mentioning

confidence: 99%

Section: Fig 1-application Matrix Of Nanotechnology In Food Science mentioning

confidence: 99%

Section: Fig 1-application Matrix Of Nanotechnology In Food Science mentioning

confidence: 99%

See 1 more Smart Citation

Nano-biotechnology breakthrough and food-packing industry- A Review

Helmy

2016

MBJ

View full text Add to dashboard Cite

show abstract

“…Bacterial toxins are proteinaceous or nonproteinaceous components that can interact with and destroy host cells or damage them. Bacterial toxins are commonly classified into exotoxins (produced by both Gram-positive and Gram-negative bacteria cells) and endotoxins (often produced by Gram-negative bacteria; Zhu et al 2014). Exotoxins can also be classified into more types based on their structural and biological characters (Alouf 2003;Odumosu et al 2010;Zhu et al 2014).…”

Section: Introductionmentioning

confidence: 99%

Current advances in aptamer-assisted technologies for detecting bacterial and fungal toxins

et al. 2018

View full text Add to dashboard Cite

SummaryInfectious diseases are among the common leading causes of morbidity and mortality worldwide. Associated with the emergence of new infectious diseases, the increasing number of antimicrobial-resistant isolates presents a serious threat to public health and hospitalized patients. A microbial pathogen may elicit several host responses and use a variety of mechanisms to evade host defences. These methods and mechanisms include capsule, lipopolysaccharides or cell wall components, adhesions and toxins. Toxins inhibit phagocytosis, cause septic shock and host cell damages by binding to host surface receptors and invasion. Bacterial and fungal pathogens are able to apply many different toxin-dependent mechanisms to disturb signalling pathways and the structural integrity of host cells for establishing and maintaining infections Initial techniques for analysis of bacterial toxins were based on in vivo or in vitro assessments. There is a permanent demand for appropriate detection methods which are affordable, practical, careful, rapid, sensitive, efficient and economical. Aptamers are DNA or RNA oligonucleotides that are selected by systematic evolution of ligands using exponential enrichment (SELEX) methods and can be applied in diagnostic applications. This review provides an overview of aptamer-based methods as a novel approach for detecting toxins in bacterial and fungal pathogens.

show abstract

“…The electrochemical responses of THI at the SPCE were used as the analytical signals to be related with OTA concentrations from values as low as 5.6 pg·mL −1 [66]. Bacterial toxins, toxic substances produced and released by bacteria to target other bacterial or host cells, have also been determined using electrochemical affinity biosensors [67]. For example, a sandwich-type electrochemical immunoassay for ultrasensitive detection of Staphylococcal enterotoxin B (SEB) in food was developed using HRP-nanosilica-doped multiwalled carbon nanotubes (HRPSiCNTs) for signal amplification [68].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Affinity Biosensors in Food Safety

2017

View full text Add to dashboard Cite

Safety and quality are key issues of today's food industry. Since the food chain is becoming more and more complex, powerful analytical methods are required to verify the performance of food safety and quality systems. Indeed, such methods require high sensitivity, selectivity, ability for rapid implementation and capability of automatic screening. Electroanalytical chemistry has, for decades, played a relevant role in food safety and quality assessment, taking more and more significance over time in the solution of analytical problems. At present, the implementation of electrochemical methods in the food is evident. This is in a large part due to the relevant results obtained by combining the attractive advantages of electrochemical transduction strategies (in terms of relatively simple hardware, versatility, interface with automatic logging and feasibility of application outside the laboratory environment) with those from biosensors technology. Important examples of enzyme electrochemical biosensors are those dedicated to the determination of glucose, alcohol or cholesterol are important examples. In addition, other types of different electrochemical biosensing approaches have emerged strongly in the last years. Among these, the strategies involving affinity interactions have been shown to possess a large number of applications. Therefore, electrochemical immunosensors and DNA-based biosensors have been widely used to determine major and minor components in foodstuffs, providing sufficient data to evaluate food freshness, the quality of raw materials, or the origin of samples, as well as to determine a variety of compounds at trace levels related to food safety such as micotoxins, allergens, drugs residues or pathogen microorganisms. This review discusses some critical examples of the latest advances in this area, pointing out relevant methodologies related to the measurement techniques, including the use of nanostructured electrodes and strategies for signal amplification.

show abstract

Recent Developments in Antibody-Based Assays for the Detection of Bacterial Toxins

Cited by 50 publications

References 131 publications

Nano-biotechnology breakthrough and food-packing industry- A Review

Nano-biotechnology breakthrough and food-packing industry- A Review

Current advances in aptamer-assisted technologies for detecting bacterial and fungal toxins

Electrochemical Affinity Biosensors in Food Safety

Contact Info

Product

Resources

About