Recent developments by zinc based reagents/catalysts promoted organic transformations

Ghouse, Shaik Mohammed; Sreenivasulu, Chinnabattigalla; Kishore, Dakoju Ravi; Satyanarayana, Gedu

doi:10.1016/j.tet.2021.132580

Cited by 11 publications

(6 citation statements)

References 140 publications

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“…Unexpectedly, the scaffolds made from pyranoquinolinones, 10 contain the structural elements of many herbal alkaloidal extracts, including Flindersine (A), Simulenoline (B) and Haujiaosimuline (C), (Figure 1). In addition, pyranoquinolones, 10 has intriguing biological qualities, like bacteriostatic, anti‐inflammatory and, anti‐allergic capabilities, which make it a worthwhile supplement (Table 2) [61].…”

Section: Synthesis Strategies For Pyranoquinolone Derivatives and The...mentioning

confidence: 99%

Pyranoquinolone derivatives: A potent multi‐targeted pharmacological scaffold

Uppal

Mir

Chawla

et al. 2022

Journal of Heterocyclic Chem

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The search for new heterocyclic compounds with potential bioactivities continues despite the fact that extensive work has already been done on pyranoquinolones. Researchers throughout the world have used the pyranoquinolone nucleus extensively to generate a wide variety of bioactive heterocycles that target a wide spectrum of biological targets. An in-depth investigation into possible pyranoquinolone derivatives and their pharmacological importance is the focus of this overview of synthetic techniques. Researchers and medicinal chemists can benefit from this review by developing new pyranoquinolone nucleus leads that are very effective and have fewer adverse effects than existing ones.

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Section: Synthesis Strategies For Pyranoquinolone Derivatives and The...mentioning

confidence: 99%

Pyranoquinolone derivatives: A potent multi‐targeted pharmacological scaffold

Uppal

Mir

Chawla

et al. 2022

Journal of Heterocyclic Chem

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“…Zinc(II) is acidic in nature, as the 4s and 4p orbitals are empty and available for coordination [1], whereas the 3d orbitals are full and, unlike many other late transition metals, redox-stable. This makes zinc(II) salts good catalysts for many reactions [2]: among others, we can remember the Friedel-Craft benzylation of benzenes [3], the Biginelli reaction [4], alkyne hydrogenation to alkenes [5], activation of CO 2 [6], trans-amidation [7], and trans-esterification [8]. The latter has been also extended to polyester synthesis and degradation [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Zinc(II)-Based Lewis/Brønsted Acidic Deep Eutectic Solvents

Pelosi,

Quaranta,

Rollo

et al. 2023

Molecules

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Lewis/Brønsted acidic deep eutectic solvents (LBDESs) are a recent class of solvents that combine the two types of acidity. In some cases, this synergy leads to enhanced catalytic properties for many reactions and applications. For this reason, it is important to discover more LBDESs. In this work, we prepared and characterized four different zinc(II)-based LBDESs, mixing ZnCl2 and various Brønsted acids: acetic, glycolic, levulinic, and formic acids. Apart from the latter, for which the corresponding DES is not thermally stable, the samples have been characterized in terms of density, viscosity, and conductivity. Notably, as zinc(II) is a diamagnetic metal, all of them are suitable for NMR spectroscopy, for example, for kinetic and mechanistic studies.

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“…24,25 Additionally, zinc, which is available in abundance, cost-efficient, and eco-friendly, is an alternative to noble metal catalysts in various organic transformations. 26 Despite the use of several zinc complexes as active catalysts in hydrosilylations of carbonyls 27,28 and imines, 29 their use in the reduction of esters, 30,31 amides, 32 and CO 2 [33][34][35] has been scarcely reported. In 2010, Beller et al reported a chemoselective hydrosilylation of a tertiary amide using triethoxysilane, catalyzed by zinc acetate.…”

Section: Introductionmentioning

confidence: 99%