Recent chemical syntheses of bacteria related oligosaccharides using modern expeditious approaches

Cyanomethyl (CNMe) ether: an orthogonal protecting group for saccharides

“…1 With the growing relevance of this class of biomolecules in pharmaceutical sciences, it is pertinent to obtain glycoconjugates in significant amounts for identifying their exact biological properties and further develop them as promising therapeutics. 2,3 Among the various criteria set for the formation of the oligomers, strategic employment of protecting groups (PGs) on the polyhydroxylated scaffolds is a standard operation. 4 While a wide range of such protecting groups have been well explored in synthetic chemistry, orthogonal PGs have attracted immense attention in sequential glycosylation strategies for oligosaccharide syntheses.…”