Recent cancer incidence trends in Ukraine and short-term predictions to 2022

Ryzhov, Anton; Bray, Freddie; Ferlay, Jacques; Федоренко, З П; Goulak, Liudmyla; Gorokh, Yevgeniy; Soumkina, Olena; Michailovich, Yuriy; Znaor, Ariana

doi:10.1016/j.canep.2019.101663

Cited by 26 publications

(17 citation statements)

References 30 publications

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“…The CCI was computed based on ICD-10 codes and was used as a summary measure. 29 CCI scores were classified as low (index score = 0), moderate (index score = 1-2), or high (index score ≥3), based on definitions from previous studies and to increase the statistical power.…”

Section: Methodsmentioning

confidence: 99%

Association Between Statins and the Risk of Kidney Cancer Incidence and Mortality Using the Korean National Health Insurance Claims Database

Kim

Ahn

2022

Cancer Control

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Background Conflicting results have been reported regarding the potential preventive effects of statins on the risk of cancer. This study investigated the associations of statin use with the incidence and mortality of kidney cancer in South Korea. Methods In this retrospective population-based cohort study using the National Health Insurance claims database, we compared patients aged 45-70 years who had used statins for at least 6 months to non-statin users matched by age and sex from 2005 to June 2013. The main outcomes were kidney cancer incidence and mortality according to statin use. Cox proportional hazard regression was used to calculate the adjusted hazard ratios (aHRs) and 95% confidence intervals (95% CIs). Results In the cohort of 1 008 101 people, the aHRs for the association between statin use and the outcomes were .84 (95% CI: 0.71-.99) for kidney cancer incidence and .65 (95% CI: 0.41-.98) for kidney cancer mortality. In the matched cohort of 337 578, the risk per 1000 people of cancer incidence and mortality was 1.63, 1.07, and .24, .17 in statin users and non-users, respectively. In matched cohort, the risk of kidney cancer incidence and mortality decreased, but it is not statistically significant. Also, there was no linear relationship with increased doses. Conclusion Statin use might be associated with a decreased risk of kidney cancer incidence and mortality, but it showed no statistical significance. This study was a large-scale analysis, however, further studies that are larger and multinational in scope are needed to confirm the beneficial effects of statins on survival.

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Section: Methodsmentioning

confidence: 99%

Association Between Statins and the Risk of Kidney Cancer Incidence and Mortality Using the Korean National Health Insurance Claims Database

Kim

Ahn

2022

Cancer Control

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“…Cancer is the second leading cause of death in the world accounting for nearly 10 million deaths in 2020. 1 Cancer is a lethal cluster of diseases described by overexcited cell division. 2 As stated by the report issued by the World Health Organization in 2018, the number of cancer cases in the world is estimated to increase to 22 million by 2030.…”

Section: Introductionmentioning

confidence: 99%

New pyrimidine-5-carbonitrile derivatives as EGFR inhibitors with anticancer and apoptotic activities: design, molecular modeling and synthesis

2022

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“…Ukraine has a population of 44 million, with cancer epidemiology rates that are similar to other European countries. 2 Many refugees have moved on from those countries to other European countries. Some of these refugees have medical conditions, including cancer, that require treatment.…”

Section: Introductionmentioning

confidence: 99%

Radiation Oncology in a Humanitarian Emergency: Experience with Ukrainian Refugees at 2 Cancer Centers in Poland and Italy

Malicki

Franco

Milecki

et al. 2022

Advances in Radiation Oncology

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Recent cancer incidence trends in Ukraine and short-term predictions to 2022

Cited by 26 publications

References 30 publications

Association Between Statins and the Risk of Kidney Cancer Incidence and Mortality Using the Korean National Health Insurance Claims Database

Association Between Statins and the Risk of Kidney Cancer Incidence and Mortality Using the Korean National Health Insurance Claims Database

New pyrimidine-5-carbonitrile derivatives as EGFR inhibitors with anticancer and apoptotic activities: design, molecular modeling and synthesis

Radiation Oncology in a Humanitarian Emergency: Experience with Ukrainian Refugees at 2 Cancer Centers in Poland and Italy

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