Recent advances with cobalt-mediated asymmetric hydrogenations

Cobalt-Catalyzed Efficient Asymmetric Hydrogenation of α-Primary Amino Ketones

“…Transition-metal-catalyzed asymmetric hydrogenation (AH) represents one of the most elegant ways to construct chiral molecules. , Compared to the well-developed rare metal-catalyzed version, earth-abundant metal-catalyzed asymmetric hydrogenation has attracted growing interest and already witnessed competent or even more remarkable results. − Within this newly emerging field, cobalt-catalyzed asymmetric hydrogenation has developed precipitously in the past decade. − …”

“… 3 − 9 Within this newly emerging field, cobalt-catalyzed asymmetric hydrogenation has developed precipitously in the past decade. 10 − 12 …”