Recent advances using MXenes in biomedical applications

Lee, I-Chi; Li, Yi-Chen Ethan; Thomas, James L.; Lee, Mei-Hwa; Lin, Hung-Yin

doi:10.1039/d3mh01588b

Cited by 10 publications

(1 citation statement)

References 219 publications

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“…However, novel applications include wastewater treatment and solar cells. [73][74][75][76] In addition, MXene and its derivatives are now gradually entering the biomedical science and drug delivery fields due to their excellent biocompatibility, great physicochemical-biological properties, contact-killing capacity, phototherapy activity and non-toxic behaviour. As reported, MXene can induce oxidative stress, resulting in cell damage, and can be applied as an antibacterial agent against various pathogens.…”

Section: Mxene (Metal Carbide)mentioning

confidence: 99%

Carbon-based two-dimensional (2D) materials: a next generation biocidal agent

Talreja,

Chuahan,

Ashfaq

2024

Mater. Adv.

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Section: Mxene (Metal Carbide)mentioning

confidence: 99%

Carbon-based two-dimensional (2D) materials: a next generation biocidal agent

Talreja,

Chuahan,

Ashfaq

2024

Mater. Adv.

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Ta₄C₃ Nanosheets as a Novel Therapeutic Platform for Photothermal‐Driven ROS Scavenging and Immune Activation against Antibiotic‐Resistant Infections in Diabetic Wounds

Wang,

Yang,

et al. 2024

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The accumulation of excessive reactive oxygen species (ROS) and recurrent infections with drug‐resistant bacteria pose significant challenges in diabetic wound infections, often leading to impediments in wound healing. Addressing this, there is a critical demand for novel strategies dedicated to treating and preventing diabetic wounds infected with drug‐resistant bacteria. Herein, 2D tantalum carbide nanosheets (Ta4C3 NSs) have been synthesized through an efficient and straightforward approach, leading to the development of a new, effective nanoplatform endowed with notable photothermal properties, biosafety, and diverse ROS scavenging capabilities, alongside immunogenic attributes for diabetic wound treatment and prevention of recurrent drug‐resistant bacterial infections. The Ta4C3 NSs exhibit remarkable photothermal performance, effectively eliminating methicillin‐resistant Staphylococcus aureus (MRSA) and excessive ROS, thus promoting diabetic wound healing. Furthermore, Ta4C3 NSs enhance dendritic cell activation, further triggering T helper 1 (TH1)/TH2 immune responses, leading to pathogen‐specific immune memory against recurrent MRSA infections. This nanoplatform, with its significant photothermal and immunomodulatory effects, holds vast potential in the treatment and prevention of drug‐resistant bacterial infections in diabetic wounds.

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Towards a new era of 2D materials-based multifunctional composite films: From innovation to evolution

Khalid,

Umer

2024

Advanced Industrial and Engineering Polymer Research

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Recent advances using MXenes in biomedical applications

Abstract: An MXene is a novel two-dimensional transition metal carbide or nitride, with a typical formula of Mn+1XnTX (M= transition metals, X= carbon or nitrogen, T= functional groups). MXenes have gained...

Cited by 10 publications

References 219 publications

Carbon-based two-dimensional (2D) materials: a next generation biocidal agent

Carbon-based two-dimensional (2D) materials: a next generation biocidal agent

Ta₄C₃ Nanosheets as a Novel Therapeutic Platform for Photothermal‐Driven ROS Scavenging and Immune Activation against Antibiotic‐Resistant Infections in Diabetic Wounds

Towards a new era of 2D materials-based multifunctional composite films: From innovation to evolution

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Recent advances using MXenes in biomedical applications

Abstract: An MXene is a novel two-dimensional transition metal carbide or nitride, with a typical formula of Mn+1XnTX (M= transition metals, X= carbon or nitrogen, T= functional groups). MXenes have gained...

Cited by 10 publications

References 219 publications

Carbon-based two-dimensional (2D) materials: a next generation biocidal agent

Carbon-based two-dimensional (2D) materials: a next generation biocidal agent

Ta4C3 Nanosheets as a Novel Therapeutic Platform for Photothermal‐Driven ROS Scavenging and Immune Activation against Antibiotic‐Resistant Infections in Diabetic Wounds

Towards a new era of 2D materials-based multifunctional composite films: From innovation to evolution

Contact Info

Product

Resources

About

Ta₄C₃ Nanosheets as a Novel Therapeutic Platform for Photothermal‐Driven ROS Scavenging and Immune Activation against Antibiotic‐Resistant Infections in Diabetic Wounds