Recent advances progress in radiotherapy for breast cancer after breast-conserving surgery: a review

Abstract

Adjuvant radiotherapy after breast-conserving surgery has become an integral part of the treatment of breast cancer. In recent years, the development of radiotherapy technology has made great progress in this field, including the comparison of the curative effects of various radiotherapy techniques and the performance of the segmentation times. The choice of radiotherapy technology needs to be co-determined by clinical evidence practice and evaluated for each individual patient to achieve precision radiotherapy. This article discusses the treatment effects of different radiotherapy, techniques, the risk of second cancers and short-range radiation therapy techniques after breast-conserving surgery such as hypo fractionated whole breast irradiation and accelerated partial breast irradiation. The choice of radiotherapy regimen needs to be based on the individual condition of the patient, and the general principle is to focus on the target area and reduce the irradiation of the normal tissues and organs. Short-range radiotherapy and hypofractionated are superior to conventional radiotherapy and are expected to become the mainstream treatment after breast-conserving surgery.

Lung-heart toxicity in a randomized clinical trial of hypofractionated image guided radiation therapy for breast cancer

“…Another gain lays in the better dose distribution, delivering a more homogeneous dose to the breast, but less to the surrounding tissues. Other techniques reviewed in recent issues of the journal, such as prone positioning, breath hold, particles for various indications ( 45 – 48 ), can reduce the dose to the heart and other organs too. The present study provides sustained long term information that will be useful for future studies to identify the most cost-effective way to reduce lung-heart doses, and to evaluate alternative treatment paradigms such as partial breast irradiation or intraoperative radiation therapy.…”