Recent advances on the thermal properties and applications of nanofluids: From nanomedicine to renewable energies

Souza, Reinaldo Rodrigues de; Gonçalves, Inês; Rodrigues, Raquel; Minas, Graça; Miranda, J. M.; Moreira, A.L.N.; Lima, Rui; Coutinho, Gonçalo; Pereira, José; Moita, Ana S.

doi:10.1016/j.applthermaleng.2021.117725

Cited by 55 publications

(16 citation statements)

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“… PDMS applications: ( a ) in microfluidic devices to assess motions and deformations of red blood cells (RBCs) from healthy donors and pathological patients [ 36 ]; ( b ) in microchannel networks to investigate gas embolism [ 38 ]; ( c ) with a flow-focusing technique to generate micro-sized PDMS particles [ 44 ]; ( d ) with PDMS biomodels to assess the blood flow behavior in aneurisms [ 39 ]. …”

Section: Figurementioning

confidence: 99%

“…It is a highly used silicon-based polymer with good chemical and thermal stability [ 4 , 15 , 16 , 17 ], biocompatibility [ 18 , 19 , 20 ], corrosion resistance [ 21 , 22 ], flexibility [ 23 , 24 , 25 ], repeatability [ 26 ], a low cost [ 27 ], ease of use, chemically inertia, hyperplastic characteristics, and gas permeability [ 3 , 28 ]. Thus, PDMS has been used in several fields and systems (see Figure 1 ), such as microfluidics and nanofluidics [ 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 ], biomodels [ 38 , 39 ], organ-on-a-chip platforms [ 40 , 41 ], blood analogues [ 42 , 43 , 44 , 45 , 46 ], electronic components [ 47 ], membranes for filtering and pervaporation [ 48 , 49 , 50 ], sensors [ 51 , 52 , 53 ], optical and thermal devices [ 54 , 55 , 56 ], coatings [ 57 , 58 , 59 ], etc. However, several PDMS applications can be compromised due to its low mechanical properties, such as low elasticity modulus and...…”

Section: Introductionmentioning

confidence: 99%

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Polydimethylsiloxane Composites Characterization and Its Applications: A Review

et al. 2021

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Polydimethylsiloxane (PDMS) is one of the most promising elastomers due its remarkable proprieties such as good thermal stability, biocompatibility, corrosion resistance, flexibility, low cost, ease of use, chemically inertia, hyperplastic characteristics, and gas permeability. Thus, it can be used in areas such as microfluidic systems, biomedical devices, electronic components, membranes for filtering and pervaporation, sensors, and coatings. Although pure PDMS has low mechanical properties, such as low modulus of elasticity and strength, it can be improved by mixing the PDMS with other polymers and by adding particles or reinforcements. Fiber-reinforced PDMS has proved to be a good alternative to manufacturing flexible displays, batteries, wearable devices, tactile sensors, and energy harvesting systems. PDMS and particulates are often used in the separation of liquids from wastewater by means of porosity followed by hydrophobicity. Waxes such as beeswax and paraffin have proved to be materials capable of improving properties such as the hydrophobic, corrosion-resistant, thermal, and optical properties of PDMS. Finally, when blended with polymers such as poly (vinyl chloride-co-vinyl acetate), PDMS becomes a highly efficient alternative for membrane separation applications. However, to the best of our knowledge there are few works dedicated to the review and comparison of different PDMS composites. Hence, this review will be focused on PDMS composites, their respective applications, and properties. Generally, the combination of elastomer with fibers, particles, waxes, polymers, and others it will be discussed, with the aim of producing a review that demonstrates the wide applications of this material and how tailored characteristics can be reached for custom applications.

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Section: Figurementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Polydimethylsiloxane Composites Characterization and Its Applications: A Review

et al. 2021

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“…A frequently used material is polydimethylsiloxane (PDMS) [19,20]. PDMS has been widely used in different kinds of research fields [21][22][23][24][25][26][27] due to its excellent properties and ability to replicate reliable geometries, in addition to its high flexibility, low glass transition temperature, good chemical resistance, excellent thermal stability and biocompatibility [28].…”

Section: Introductionmentioning

confidence: 99%

Fluid Flow and Structural Numerical Analysis of a Cerebral Aneurysm Model

Souza

Carvalho

et al. 2022

Fluids

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Intracranial aneurysms (IA) are dilations of the cerebral arteries and, in most cases, have no symptoms. However, it is a very serious pathology, with a high mortality rate after rupture. Several studies have been focused only on the hemodynamics of the flow within the IA. However, besides the effect of the flow, the development and rupture of the IA are also associated with a combination of other factors such as the wall mechanical behavior. Thus, the objective of this work was to analyze, in addition to the flow behavior, the biomechanical behavior of the aneurysm wall. For this, CFD simulations were performed for different Reynolds numbers (1, 100, 500 and 1000) and for two different rheological models (Newtonian and Carreau). Subsequently, the pressure values of the fluid simulations were exported to the structural simulations in order to qualitatively observe the deformations, strains, normal stresses and shear stress generated in the channel wall. For the structural simulations, a hyperelastic constitutive model (5-parameter Mooney–Rivlin) was used. The results show that with the increase in the Reynolds number (Re), the recirculation phenomenon is more pronounced, which is not seen for Re = 1. The higher the Re, the higher the strain, displacement, normal and shear stresses values.

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“…During the last 20 years, the progress of microfluidic systems has attracted several researchers and has been applied in several fields ranging from renewable energy to nanomedicine [ 6 , 7 , 8 , 9 ]. In the field of biomedical applications, novel advanced microfluidic devices comprising biomodels have been developed to recreate the microenvironments and cellular functions and interactions present in certain organs.…”

Section: Introductionmentioning

confidence: 99%

Organ-on-a-Chip Platforms for Drug Screening and Delivery in Tumor Cells: A Systematic Review

Gonçalves

Carvalho

Rodrigues

et al. 2022

Cancers

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The development of cancer models that rectify the simplicity of monolayer or static cell cultures physiologic microenvironment and, at the same time, replicate the human system more accurately than animal models has been a challenge in biomedical research. Organ-on-a-chip (OoC) devices are a solution that has been explored over the last decade. The combination of microfluidics and cell culture allows the design of a dynamic microenvironment suitable for the evaluation of treatments’ efficacy and effects, closer to the response observed in patients. This systematic review sums the studies from the last decade, where OoC with cancer cell cultures were used for drug screening assays. The studies were selected from three databases and analyzed following the research guidelines for systematic reviews proposed by PRISMA. In the selected studies, several types of cancer cells were evaluated, and the majority of treatments tested were standard chemotherapeutic drugs. Some studies reported higher drug resistance of the cultures on the OoC devices than on 2D cultures, which indicates the better resemblance to in vivo conditions of the former. Several studies also included the replication of the microvasculature or the combination of different cell cultures. The presence of vasculature can influence positively or negatively the drug efficacy since it contributes to a greater diffusion of the drug and also oxygen and nutrients. Co-cultures with liver cells contributed to the evaluation of the systemic toxicity of some drugs metabolites. Nevertheless, few studies used patient cells for the drug screening assays.

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Recent advances on the thermal properties and applications of nanofluids: From nanomedicine to renewable energies

Cited by 55 publications

References 147 publications

Polydimethylsiloxane Composites Characterization and Its Applications: A Review

Polydimethylsiloxane Composites Characterization and Its Applications: A Review

Fluid Flow and Structural Numerical Analysis of a Cerebral Aneurysm Model

Organ-on-a-Chip Platforms for Drug Screening and Delivery in Tumor Cells: A Systematic Review

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