2023
DOI: 10.1016/j.bea.2023.100080
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Recent advances of nanobubble-based systems in cancer therapeutics: A Review

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Cited by 8 publications
(9 citation statements)
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“…24 In order to overcome the abovementioned shortcomings of phototherapy, efforts have been focused on the development of PSfunctionalized composite materials for use in synergic phototherapy treatments involving both PDT and PTT 25,26 ; yet, the creation of nanocomposites involves a very complicated procedure with difficulties in the precise component control. 27,28 Porphyrins, featuring the macrocyclic 18-electron conjugated structure, 29,30 are among the most examined macrocyclic conjugated structures with promising applicability in the biomedical field in view of their adjustable structures and spectral profile, which led to the phototherapy studies on porphyrin derivatives since 1975. 11 Over the last two decades, strategies have been proposed for the phototherapeutic implementation of porphyrins, such as the modification of the porphyrin macrocyclic ring and the formation of J-nanoaggregates by self-assembly to realize the redshift of Q-band absorption.…”
Section: Introductionmentioning
confidence: 99%
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“…24 In order to overcome the abovementioned shortcomings of phototherapy, efforts have been focused on the development of PSfunctionalized composite materials for use in synergic phototherapy treatments involving both PDT and PTT 25,26 ; yet, the creation of nanocomposites involves a very complicated procedure with difficulties in the precise component control. 27,28 Porphyrins, featuring the macrocyclic 18-electron conjugated structure, 29,30 are among the most examined macrocyclic conjugated structures with promising applicability in the biomedical field in view of their adjustable structures and spectral profile, which led to the phototherapy studies on porphyrin derivatives since 1975. 11 Over the last two decades, strategies have been proposed for the phototherapeutic implementation of porphyrins, such as the modification of the porphyrin macrocyclic ring and the formation of J-nanoaggregates by self-assembly to realize the redshift of Q-band absorption.…”
Section: Introductionmentioning
confidence: 99%
“…24 In order to overcome the abovementioned shortcomings of phototherapy, efforts have been focused on the development of PS-functionalized composite materials for use in synergic phototherapy treatments involving both PDT and PTT 25,26 ; yet, the creation of nanocomposites involves a very complicated procedure with difficulties in the precise component control. 27,28…”
Section: Introductionmentioning
confidence: 99%
“…Unfortunately, the use of such treatment modalities is limited due to their adverse side effects such as higher toxic offtargeted effects on the body and the development of drug resistance. 2,3 According to recent research, utilizing combined treatment modalities will result in minimal side effects and greater efficacy than utilizing a single therapy. 4 Nanotechnology is used in various biomedical applications due to its excellent physicochemical and targeting properties.…”
Section: Introductionmentioning
confidence: 99%
“…Despite its advantages, chemotherapy is limited in solid tumors because of its penetration depth and poor targeting ability. Unfortunately, the use of such treatment modalities is limited due to their adverse side effects such as higher toxic off-targeted effects on the body and the development of drug resistance. , …”
Section: Introductionmentioning
confidence: 99%
“…From a practical perspective, the possibility to convert light into vapor has been exploited in several scientific areas, including nanoparticle-assisted cancer therapy, nano- and microfluid manipulation, , and photoacoustic imaging. Due to the explosive nature of the generated plasmonic nanobubbles, intense acoustic waves are emitted, an effect which may be exploited in the destruction of biological cellular components at the local scale. …”
Section: Introductionmentioning
confidence: 99%