Recent advances in the synthesis of trifluoromethyl-containing heterocyclic compounds via trifluoromethyl building blocks
Yaopeng Liu,
Qingyu Tian,
Jin Ge
et al.
Abstract:Trifluoromethylated heterocyclic compounds have played an increasingly significant role in pharmaceuticals, agrochemicals, and materials. This is due to the introduction of trifluoromethyl could enhance the lipophilicity, metabolic stability, and pharmacokinetic...
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