Recent Advances in the Production, Analysis, and Application of Galacto-Oligosaccharides

Iqbal, Muhammad Waheed; Riaz, Tahreem; Mahmood, Shahıd; Liaqat, Humna; Mushtaq, Anam; Khan, Sonia; Amin, Sabahat; Qi, Xianghui

doi:10.1080/87559129.2022.2097255

Cited by 11 publications

(4 citation statements)

References 157 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various biotechnological technologies, such as immobilizing or recombinant enzymes, have enhanced production [33]. GOS is also often used in milkbased products and infant formulas to mimic the effects of breast milk oligosaccharides because it is physiologically similar to breast milk [34]. The benefits of GOS include selective stimulation of beneficial microorganisms, reduced production of toxic substances, improved immune response, increased mineral absorption, and reduced severity of obesity and diabetes (Figure 2) [35].…”

Section: Galactooligosaccharides (Gos)mentioning

confidence: 99%

The Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health

Yoo,

Jung,

Kwak

et al. 2024

IJMS

View full text Add to dashboard Cite

The human gut microbiota, an intricate ecosystem within the gastrointestinal tract, plays a pivotal role in health and disease. Prebiotics, non-digestible food ingredients that beneficially affect the host by selectively stimulating the growth and/or activity of beneficial microorganisms, have emerged as a key modulator of this complex microbial community. This review article explores the evolution of the prebiotic concept, delineates various types of prebiotics, including fructans, galactooligosaccharides, xylooligosaccharides, chitooligosaccharides, lactulose, resistant starch, and polyphenols, and elucidates their impact on the gut microbiota composition. We delve into the mechanisms through which prebiotics exert their effects, particularly focusing on producing short-chain fatty acids and modulating the gut microbiota towards a health-promoting composition. The implications of prebiotics on human health are extensively reviewed, focusing on conditions such as obesity, inflammatory bowel disease, immune function, and mental health. The review further discusses the emerging concept of synbiotics—combinations of prebiotics and probiotics that synergistically enhance gut health—and highlights the market potential of prebiotics in response to a growing demand for functional foods. By consolidating current knowledge and identifying areas for future research, this review aims to enhance understanding of prebiotics’ role in health and disease, underscoring their importance in maintaining a healthy gut microbiome and overall well-being.

show abstract

Section: Galactooligosaccharides (Gos)mentioning

confidence: 99%

The Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health

Yoo,

Jung,

Kwak

et al. 2024

IJMS

View full text Add to dashboard Cite

show abstract

“…Occasionally, small quantities of galactooligosaccharides (GAOS) and glucooligosaccharides (GOS) are produced, with their concentration and DP affected by the severity factor. This underscores the significance of precise control over temperature and time to achieve desired product specifications [32]. Comparative analysis shows that different materials necessitate distinct severity factors for optimal XOS production.…”

Section: Utilization Of Lignocellulosic Waste Residues: Approaches An...mentioning

confidence: 99%

Revolutionizing Renewable Resources: Cutting-Edge Trends and Future Prospects in the Valorization of Oligosaccharides

Chelliah,

Kim,

Park

et al. 2024

Fermentation

View full text Add to dashboard Cite

Lignocellulosic wastes, primarily from agricultural by-products, are a renewable resource increasingly used in the sustainable production of oligosaccharides, significantly contributing to the growing bioeconomy. This innovative utilization of biological resources aligns with the global shift towards sustainable development, focusing on creating products such as food, feed, and bioenergy from renewable sources. Oligosaccharides, specialized carbohydrates, are synthesized either chemically or more eco-friendly, biologically. Biological synthesis often involves enzymes or whole-cell systems to transform lignocellulosic wastes into these valuable sugars. As functional food supplements, oligosaccharides play a crucial role in human and animal health. They serve as prebiotics, indigestible components that promote the proliferation of beneficial gut microbiota, especially within the colon. This positive impact on gut flora is essential for boosting the immune system and regulating physiological functions. Important prebiotics, including galactooligosaccharides (GOS), xylooligosaccharides (XOS), fructooligosaccharides (FOS), mannan-oligosaccharides (MOS), and isomaltooligosaccharides (IMOS), are produced through methods involving enzymes or the use of whole cells, with agricultural waste as substrates. Recent advancements focus on refining these biological processes for oligosaccharide synthesis using lignocellulosic substrates, emphasizing the principles of a circular bioeconomy, which promotes resource reuse and recycling. This review highlights the potential and challenges in the biological synthesis of oligosaccharides from renewable resources. It underscores the need for innovation in process optimization and commercialization strategies to fully exploit lignocellulosic wastes. This approach not only contributes to sustainable product development, but also opens new avenues for the profitable and environmentally friendly utilization of agricultural residues, marking a significant step forward in the bio-based industry.

show abstract

“…When we say that the body acts as a machine, then food acts as fuel, and the activity of the machine depends on the quality and quantity of fuel. In the same way, food plays a major role in the maintenance of various systems of the body, including the immune system, which is the major defense system to protect and fight against pathogens, including nCV-2019 [42,43]. Those patients have a strong immune system in their body that can fight against this lethal nCV-2019.…”

Section: Role Of Immune System In Combating Viral Infectionmentioning

confidence: 99%

Implications of Novel Corona Virus–2019 and Perspective of Diet Therapy as an Immune Booster: A Review

Iqbal¹,

Riaz²,

Leghari³

et al. 2022

MPNFS

View full text Add to dashboard Cite

show abstract

Recent Advances in the Production, Analysis, and Application of Galacto-Oligosaccharides

Cited by 11 publications

References 157 publications

The Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health

The Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health

Revolutionizing Renewable Resources: Cutting-Edge Trends and Future Prospects in the Valorization of Oligosaccharides

Implications of Novel Corona Virus–2019 and Perspective of Diet Therapy as an Immune Booster: A Review

Contact Info

Product

Resources

About