Recent advances in the Biosynthesis of Zirconium Oxide Nanoparticles and their Biological Applications

Abstract

A critical milestone in nano-biotechnology is establishing reliable and ecological friendly methods for fabricating metal oxide NPs. Because of their great biodegradable, electrical, mechanical, and optical qualities, zirconia NPs (ZrO2NPs) attract much interest among all zirconia NPs (ZrO2NPs). Zirconium oxide (ZrO2) has piqued the interest of researchers throughout the world, particularly since the development of methods for the manufacture of nano-sized particles. An extensive study into the creation of nanoparticles utilizing various synthetic techniques and their potential uses has been stimulated by their high luminous efficiency, wide bandgap, and high exciton binding energy. Zirconium dioxide nanoparticles may be used as antimicrobial and anticancer agents in food packaging. In response to the growing interest in nano ZrO2, researchers invented and developed methods for synthesizing nanoparticles. ZrO2 nanocomposites with various morphologies have recently been created using biological (green chemistry) methods. Microbes and plants both contribute to the production of zirconia in the laboratory. Capping and stabilizing agents are provided by the biomolecules found in plant extracts, whereas microorganisms provide enzymes as capping and stabilizing agents (intracellular or extracellular). It is possible to analyze the nanoparticles produced using a variety of analytical approaches, including ultraviolet-visible spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FT-IR). When applied to bacteria (both Gram-positive and Gram-negative) and fungi, ZrO2NPs show promising antibacterial capabilities. Normal and malignant cells are sensitive to ZrO2 nanoparticles, which can be explained by the generation of reactive oxygen (ROS). This work discusses and describes many ways of producing ZrO2 nanoparticles, their properties, and various application possibilities.

Breaking Barriers in Eco-Friendly Synthesis of Plant-Mediated Metal/Metal Oxide/Bimetallic Nanoparticles: Antibacterial, Anticancer, Mechanism Elucidation, and Versatile Utilizations

“…The body's natural antioxidant defence mechanism is always at work, scavenging ROS by binding to and neutralizing free radicals. However, producing ROS over the physiological threshold activates controlled cell death processes, which can be used in a variety of cancer treatments [263,264]. Previously reported research indicated that the ROS pathway was required for ZrO 2 NPs to cause cytotoxicity in a variety of cancer cell lines including A549, HCT116, and MCF7 [265].…”

إنتاج جسيمات الفضة النانوية المُصنَّعة حيوياً من فطر Metarhizium anisopliae لمعالجة الملوثات النفطية في الماء

“…Nanotechnology technique deals with particles ranging from 1 to 100 nm 7 . Nanomaterials differ from their larger counterparts in terms of their physical, chemical, and structural characteristics, the nanomaterials' extraordinary magnetic, electrical, and optical characteristics and surface activity are due to their nanoscale shape and size 8 .…”

Corporate Investment Decisions in Changing Interest Rate Environments

“…Zirconium oxide nanoparticles have applications as antimicrobial and anticancer agents in food packaging. They exhibit antibacterial properties against both Grampositive and Gram-negative bacteria [9]. The present study intends to synthesise Zirconium incorporated, pectin-based nanoparticles for prospective antimicrobial and water purification applications.…”