Recent advances in single-benzene-based fluorophores: physicochemical properties and applications

Abstract

The recently reported physicochemical properties and applications of single-benzene-based fluorophores (SBBFs) are summarized.

Progress and Perspective of Solid-State Organic Fluorophores for Biomedical Applications

“…In the past 20 years, studies have reported the high potential of SSOFs for biomedical applications and attributed it to their resistance to self-quenching, high photostability, and long-term in situ tracking. − Thus, this Perspective will focus on the different properties (e.g., tunable fluorescence, signal-to-background ratio, and long-term tracking) and bioapplications (e.g., bioimaging, biosensing, and disease diagnosis and treatment) of conventional, aggregation-induced emissive, and precipitating SSOFs. Notably, it will provide insights on the key advances in the field of biomedical research, relevant prospects of SSOFs, and limitations faced in the development of SSOFs with the aim that the information will encourage researchers to develop SSOFs for their effective application in the field of biomedicine.…”

Visual organophosphate vapor sensing by dibenzylidine derivatives exhibiting intramolecular charge transfer and aggregation induced emission

“…8 Luminescence modulation in such materials has been accomplished in many instances through attaching electron donating or accepting substituents on molecular skeletons, which allow modulation of electron densities and concomitant optical properties. 9 π-conjugated organic luminophores displaying electron donor (D) and acceptor (A) subunits including substituted phenyls, 10 stilbenes, 11 and tetra phenyl-ethylene derivatives 12 have been reported. Exploiting and controlling the optical properties of organic luminophores, however, face conceptual and technical challenges.…”

Development of a fluorescent nanoprobe based on an amphiphilic single-benzene-based fluorophore for lipid droplet detection and its practical applications

“…SBBF has a push-pull system in a compact benzene ring and has distinctive optical properties such as polarity-/pH-insensitive solvatochromic properties, high fluorescence quantum yield, and high biocompatibility. 45 BMeS-Ali has a simple structure and is readily obtained by one-step synthesis from BMeS-p-A dye. 46 BMeS-Ali consists of hydrophilic (-NH 2 ) and hydrophobic (-C 12 H 25 ) moieties in the SBBF backbone and exists as a liposomal micelle nanostructure in aqueous media.…”