Recent Advances in Nonprecious Metal Catalysis

Haibach, Michael C.; Ickes, Andrew R.; Wilders, Alison M.; Shekhar, Shashank

doi:10.1021/acs.oprd.0c00367

Cited by 22 publications

(14 citation statements)

References 97 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies by several research groups, including those of MacMillan, Weix, Reisman, Gong, and others, have established the feasibility and synthetic effectiveness of this chemistry, as highlighted earlier in this review series. 3,4 MacMillan described the use of silanemediated bromine atom abstraction under dual nickel/photoredox catalysis as an alternative approach for the crosselectrophile coupling of aryl bromides and alkyl bromides. 22 Recently, MacMillan's group communicated 23 the modification of the silane substituents to amplify the electron density on an open-shell silicon group, resulting in an increased polarity that is properly tuned for the matching effect between an unactivated C−Cl bond and the silyl abstraction reagent (Scheme 11).…”

Section: ■ Recent Reports On Ni-catalyzed Reactionsmentioning

confidence: 99%

“…As part of the engagement of the Boehringer Ingelheim (BI) process chemistry group in a precompetitive space with AbbVie and Pfizer process chemists in an attempt to promote the development and applications of NPMC, a series of review articles has been initiated to highlight recent advancements in the field. The first review was authored by a team of process chemists at Pfizer and the second by a team of process chemists at AbbVie . This review is the third installment of the series and covers articles in the field of NPMC published between July and October 2020.…”

mentioning

confidence: 99%

“…The first review was authored by a team of process chemists at Pfizer 3 and the second by a team of process chemists at AbbVie. 4 This review is the third installment of the series and covers articles in the field of NPMC published between July and October 2020.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Recent Advances in Nonprecious Metal Catalysis

Buono

Nguyen

et al. 2021

Org. Process Res. Dev.

View full text Add to dashboard Cite

This review summarizes recent developments and synthetic applications of nonprecious metal catalysis (NPMC) published between July and October 2020. It is the next installment of the review series on this topic briefing recent advancements in the synthetic utility of Ni, Cu, and Fe catalysis. The continued increase in the number of publications in this area attests to the wide interest among academic and industrial research laboratories in advancing the catalytic applications of these earth-abundant metals.

show abstract

Section: ■ Recent Reports On Ni-catalyzed Reactionsmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Recent Advances in Nonprecious Metal Catalysis

Buono

Nguyen

et al. 2021

Org. Process Res. Dev.

View full text Add to dashboard Cite

show abstract

“…Over the past couple decades, the use of transition-metal-catalyzed cross-coupling reactions have become a staple within the organic chemist's arsenal of carbon-carbon and carbon-heteroatom bond-forming reactions. Catalysis, as a synthetic tool, is widely employed to accomplish transformations to produce many various pharmaceuticals, polymeric materials, and fine chemicals [1][2][3][4][5][6][7][8]. Catalysis is one of the fundamental pillars of green chemistry, the design of chemical products and processes that reduce or eliminate the use and generation of hazardous substances, as well as increase the atom economy of the reac-tion [9].…”

Section: Introductionmentioning

confidence: 99%

Iron-catalyzed domino coupling reactions of π-systems

Pounder¹,

Tam²

2021

Beilstein J. Org. Chem.

View full text Add to dashboard Cite

The development of environmentally benign, inexpensive, and earth-abundant metal catalysts is desirable from both an ecological and economic standpoint. Certainly, in the past couple decades, iron has become a key player in the development of sustainable coupling chemistry and has become an indispensable tool in organic synthesis. Over the last ten years, organic chemistry has witnessed substantial improvements in efficient synthesis because of domino reactions. These protocols are more atom-economic, produce less waste, and demand less time compared to a classical stepwise reaction. Although iron-catalyzed domino reactions require a mindset that differs from the more routine noble-metal, homogenous iron catalysis they bear the chance to enable coupling reactions that rival that of noble-metal-catalysis. This review provides an overview of iron-catalyzed domino coupling reactions of π-systems. The classifications and reactivity paradigms examined should assist readers and provide guidance for the design of novel domino reactions.

show abstract

“…Here we continue a review series initiated by a precompetitive process chemistry alliance at AbbVie, Pfizer, and Boehringer Ingelheim that highlights recent reports of nonprecious metal catalysis of interest to the pharmaceutical process development community. − This review covers articles published from March through June 2021. The nonprecious metal catalysts covered in this review include examples with Ni, Cu, Fe, Mn, Co, Ti, Mg, Zn, and K.…”

mentioning

confidence: 99%